Endothelin ELISA Kit

The endothelin peptide family consists of three isoforms, ET-1 (corresponding to the initially isolated and most predominant isoform), ET-2, and ET-3. ET-1 is a 21 amino acid peptide and is one of the most potent vasoconstritors currently known. ET-2 displays similar pharmacology to ET-1, whereas ET-3 is a weak vasoconstrictor but more potent inhibitor of platelet aggregation. Cayman's Endothelin Assay is an immunometric (i.e., sandwich) ELISA that permits endothelin measurements within the range of 7.8-250 pg/ml, typically with a limit of detection of 7.8 pg/ml. Inter- and intra-assay CV's of less than 10% may be achieved at most concentrations. This assay offers sensitive and specific analysis of endothelin in serum, plasma, urine, or cell culture media.Synonyms: ET EIA Kit. Limit of Detection: 7.8 pg/ml. Assay Range: 7.8-250 pg/ml. Cross Reactivity: (Endothelin-1) 100%, (Endothelin-2) 100%, (Endothelin-3) 100%, (VIC) 100%, (Big Endothelin) 100%. Origin: Animal/Bovine, Animal/Eel, Animal/Mouse.