Cyclin D3 (Phospho-Thr283) Colorimetric Cell-Based ELISA Kit

Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-CBCAB00408.96 96 assays (2 x 96-well microplates) - -

9 - 20 business days*

641.00€
 
Cyclin D3 (Phospho-Thr283) Colorimetric Cell-Based ELISA Kit Protein function: Regulatory... more
Product information "Cyclin D3 (Phospho-Thr283) Colorimetric Cell-Based ELISA Kit"
Cyclin D3 (Phospho-Thr283) Colorimetric Cell-Based ELISA Kit Protein function: Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex. [The UniProt Consortium]
Keywords: CCND3, G1/S-specific cyclin-D3
Supplier: Assay Genie
Supplier-Nr: CBCAB00408

Properties

Application: In-cell ELISA

Database Information

KEGG ID : K10152 | Matching products
UniProt ID : P30281 | Matching products

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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