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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay10010854-96 | 96 wells | - |
6 - 10 business days* |
661.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Three known isoforms of SREBP (sterol regulatory element binding protein) transcription factors... more
Product information "SREBP-1 Transcription Factor Assay Kit"
Three known isoforms of SREBP (sterol regulatory element binding protein) transcription factors have been characterized: SREBP-1a, SREBP-1c, and SREBP-2. SREBP-1c acts primarily to activate genes required for fatty acid synthesis, such as acetyl-CoA carboxylase, fatty acid synthase, and long chain fatty acid elongase. In addition, SREBP-1c may also contribute to the regulation of glucose uptake and synthesis through induction of glucokinase. SREBP-1c has important clinical implications in the treatment of many diseases including obesity, diabetes mellitus, insulin resistance, and non-alcoholic fatty liver disease (NAFLD). Cayman's SREBP-1 Transcription Factor Assay is a non-radioactive, sensitive method for detecting specific transcription factor DNA binding activity. SREBP-1 contained in nuclear extracts and whole cell lysates binds to a dsDNA SREBP response element immobilized to the wells of a 96-well plate. SREBP-1 is detected by addition of a specific primary antibody directed against SREBP-1. A secondary antibody conjugated to HRP is used to provide a sensitive colorimetric readout at 450 nm.Synonyms: Sterol Regulatory Element-Binding Protein-1 Assay Kit. Origin: Animal/Bovine, Animal/Rabbit, Animal/Goat.
Keywords: | Sterol Regulatory Element-Binding Protein-1 Assay Kit |
Supplier: | Cayman Chemical |
Supplier-Nr: | 10010854 |
Properties
Application: | SREBP-1 DNA binding |
Species reactivity: | human, mouse, rat |
Format: | Solid Phase |
Database Information
Handling & Safety
Storage: | -80°C |
Shipping: | -80°C (International: -80°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
|
H Phrases: | H360 |
P Phrases: | P201, P202, P280, P308+P313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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