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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay700350-96 | 96 wells | - |
6 - 10 business days* |
922.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
SET Domain-containing Protein 8 (SET8) is a methyltransferase that selectively mono-methylates... more
Product information "SET8 Methyltransferase Inhibitor Screening Assay Kit"
SET Domain-containing Protein 8 (SET8) is a methyltransferase that selectively mono-methylates histone H4 at lysine residue 20 (H4K20), an event proven to have an important role in chromatin structure and transcriptional activation. Cayman's SET8 Methyltransferase Inhibitor Screening Assay provides a convenient method for screening human SET8 inhibitors. The transfer of the methyl group from SAM by SET8 (provided in the kit) to the acceptor peptide (H4K20) generates S-adenosylhomocysteine, which is rapidly converted to urate and hydrogen peroxide (H2O2) using an enzyme mixture provided in the kit. The H2O2 formed is quantified using 10-acetyl-3,7-dihydroxyphenoxazine (ADHP) to produce the highly fluorescent compound resorufin (excitation 530-540 nm, emission 585-595 nm).Synonyms: PR-Set7, SETD8, SET domain-containing (lysine methyltransferase) 8.
Keywords: | PR-Set7, SET domain-containing (lysine methyltransferase) 8, SETD8 |
Supplier: | Cayman Chemical |
Supplier-Nr: | 700350 |
Properties
Application: | SET8 inhibitor screening |
Format: | Homog. |
Database Information
KEGG ID : | K11428 | Matching products |
UniProt ID : | Q9NQR1 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -80°C (International: -80°C) |
Signal Word: | Warning |
GHS Hazard Pictograms: |
|
H Phrases: | H227, H302, H315, H316, H319, H320 |
P Phrases: | P210, P264, P270, P280, P301+310, P302+352, P305+351+338, P321, P330, P332+313, P337+313, P362+364, P370+378, P403, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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