Anti-Insig1 (Insulin-induced Gene 1 Protein, INSIG-1)

Anti-Insig1 (Insulin-induced Gene 1 Protein, INSIG-1)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
I7655-85.100 100 µl - -

3 - 19 business days*

Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory... more
Product information "Anti-Insig1 (Insulin-induced Gene 1 Protein, INSIG-1)"
Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element-binding protein (SREBP) mediated signaling pathway. This gene is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed. Cellular Localization: Membrane , Positive Control: HepG2 lysate, Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: United States Biological
Supplier-Nr: I7655-85


Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: A synthetic peptide representing an internal region of the human protein (between residues 1-100) according to Swiss-Prot# O15503. Homology: 100% with human protein.No other significant species homology.
Purity: Purified by immunoaffinity chromatography.
Format: Affinity Purified

Database Information

Handling & Safety

Storage: -20°C (-20°C Glycerol)
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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