Products from LKT Laboratories
LKT Laboratories, Inc., in St. Paul, Minnesota, is a research and development company focussing on the synthesis, purification and isolation of small molecules. Established in 1989, LKT Labs produces and markets unique (bio-)chemicals for all types of life science research, especially for the fields of cancer and neuroscience. The products include protein kinase inhibitors as well as ion channel modulators and are used for various research applications.
More information at: www.lktlabs.com
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Harringtonin
Item number: LKT-H0169.5
An alkaloid isolated from Cephalotaxus harringtonia, and an antitumor agent.
| Keywords: | Cephalotaxine |
| Application: | Anticancer agent |
| CAS | 26833-85-2 |
| MW: | 531,6 D |
From 241.00€
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Isoflurane
Item number: LKT-I7258.250
Isoflurane is an anesthetic most commonly used in veterinary medicine. Isoflurane exhibits cardiomodulatory, neuromodulatory, and pro-inflammatory activities. In diabetic rats, isofluorane decreases cardiac force and intracellular Ca2+ amplitude. Isoflurane also increases IL-6 and NF-kappaB levels in glioma cells...
| Application: | Anesthetic [inhalation] |
| CAS | 26675-46-7 |
| MW: | 184.49 D |
From 77.00€
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Doxorubicin HCl
Item number: LKT-D5794.5
An anthracycline antibiotic, clinically used for chemotherapy of malignant tumors, particularly solid tumors. Induces apoptosis in murine and human cancer cell lines.
| Application: | Apoptosis inducer |
| CAS | 25316-40-9 |
| MW: | 579,99 D |
From 60.00€
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Antimycin A
Item number: LKT-A5378.10
White powder. An inhibitor of mitochondrial respiratory chain complex III. Induces apoptosis in cell cultures.
| Application: | Apoptosis inducer |
| CAS | 1397-94-0 |
| MW: | 548,63 D |
From 189.00€
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Rosuvastatin Calcium
Item number: LKT-R5974.25
Statin, HMG-CoA reductase inhibitor, potential NADPH oxidase and PKC inhibitor.
| Keywords: | (S-((R*,S*-(E)))- 7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2- (methyl(methylsulfonyl) amino)-5-pyrimidinyl)-3,5-dihydroxy-... |
| Application: | HMGCoA reductase inhibitor |
| CAS | 147098-20-2 |
| MW: | 1001,14 D |
From 223.00€
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Fluoxetine hydrochloride
Item number: LKT-F4780.1
A specific serotonin uptake inhibitor. It was found to exert inhibitory or stimulating effects on T-lymphocyte proliferation depending on the concentration.pH value: 5-7 (5% aqueous solution)
| Keywords: | Fluoxetine HCl |
| Application: | Serotonin uptake inhibitor |
| CAS | 59333-67-4 |
| MW: | 345,79 D |
From 127.00€
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(Z)-4-Hydroxytamoxifen
Item number: LKT-H9711.5
An active metabolite of (Z)-tamoxifen which exhibits higher potency as estrogen agonist. It binds to estrogen receptors with 8-fold higher affinity than tamoxifen.
| Application: | Metabolic studies |
| CAS | 68047-06-3 |
| MW: | 387,51 D |
From 218.00€
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Atorvastatin
Item number: LKT-A7658.10
Active hydroxy acid which works to restore cholesterol homeostasis. Inhibits HMG-CoA which leads to apoptosis of tumor cells.
| Keywords: | Atorvastatin Calcium Salt, Lipitor, Sortis: Torvast, Totalip, Xarator |
| Application: | HMG-CoA inhibitor |
| CAS | 134523-03-8 |
| MW: | 1209,42 D |
From 94.00€
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COVID-19 Research
MK2206 (dihydrochloride)
Item number: LKT-M4000.1
MK2206 is a Akt inhibitor, is also an orally bioavailable allosteric inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor MK2206 binds to and inhibits the activity of Akt in a non-ATP competitive manner, which may result in the inhibition of...
| Keywords: | MK-2206 . 2HCl, 8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-8,9-dihydro-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one... |
| Application: | AKT inhibitor |
| CAS | 1032350-13-2 |
| MW: | 445.94 D |
From 79.00€
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Allicin
Item number: LKT-A4440.1
Liquid. The main biologically active compound in garlic. It exerts various biological effects, including antiproliferative, chemopreventive, antioxidant, antihyperlipidaemic and antihypertensive effects. It has been shown to inhibit the growth of cancer cells of murine and human origin, in addition to inhibiting...
| Application: | Apoptosis inducer |
| CAS | 539-86-6 |
| MW: | 162,27 D |
From 542.00€
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Cyclosporin H
Item number: LKT-C9614.1
Cyclosporin H is a formyl peptide receptor antagonist.
| Keywords: | Csh cyclosporin, Cyclosporine H |
| Application: | Formyl peptide receptor antagonist |
| CAS | 83602-39-5 |
| MW: | 1202,61 D |
From 229.00€
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N-acetyl-L-Cysteine
Item number: LKT-A0918.25
N-Acetyl-L-cysteine exhibits antioxidative, mucolytic, anti-inflammatory, antiviral, antipsychotic, and neuromodulatory activities. N-Acetyl-L-cysteine has clinically been used to treat acetaminophen overdose, it is occasionally commercially sold as a supplement. N-Acetyl-L-cysteine acts as a scavenger of ROS,...
| Keywords: | Acetylcysteine, Brunac, Fabrol, Fluimucil, Fluprowit, Mucosil |
| Application: | Antioxidant |
| CAS | 616-91-1 |
| MW: | 163,2 D |
From 60.00€
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