Products from Indigo Biosciences
Indigo Biosciences, Inc. was founded in 2005 in State College, Pennsylvania by Dr. Jack Vanden Heuvel and Dr. Blake Peterson. It remains a privately held biosciences company offering products and services focused on in vitro toxicology and nuclear receptors. These receptors comprise a major class of therapeutic drug targets. The company’s founders leveraged their collective expertise in nuclear receptor biology, toxicology, medical chemistry and molecular biology to establish the core platform technology of the company.
More information at: www.indigobiosciences.com
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ERalpha (human) Reporter Assay Kit
Item number: IB-IB00402
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the full-length human estrogen receptor 1 (NR3A1), a ligand-dependent transcription factor commonly referred to as ERalpha. INDIGO's reporter cells include the luciferase reporter gene...
| Keywords: | ER, ESR, ESR1, ER-alpha, Estrogen receptor, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1 |
| Application: | Functional activity screening |
| Species reactivity: | human |
3,802.00€
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AR (human) Reporter Assay Kit
Item number: IB-IB03002
This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of full-length, unmodified human androgen receptor (NR3C4), a ligand-dependent transcription factor commonly referred to as AR. INDIGO's reporter cells include the luciferase...
| Keywords: | AR, DHTR, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4 |
| Application: | Functional activity screening |
| Species reactivity: | human |
3,802.00€
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GR (human) Reporter Assay Kit
Item number: IB-IB00201
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive high-level expression of full-length, unmodified human glucocorticoid receptor (NR3C1), a ligand-dependent transcription factor, commonly referred to as GR. INDIGO's reporter cells include the luciferase...
| Keywords: | GR, GRL, NR3C1, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1 |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,448.00€
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RORg (Mouse) Reporter Assay System
Item number: IB-M04001
Protein function: Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of cellular differentiation, immunity, peripheral circadian rhythm as well as lipid, steroid, xenobiotics and...
| Keywords: | TOR, Rorc, Nr1f3, Thymus orphan receptor, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, RAR-related orphan... |
| Application: | Functional activity screening |
| Species reactivity: | mouse |
From 1,448.00€
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PPARgamma (mouse/rat) Reporter Assay Kit
Item number: IB-MR00101
This nuclear receptor assay system utilizes a proprietary rodent cell line that is further engineered to express the mouse/rat peroxisome proliferator-activated receptor gamma (NR1C3, PPARG). Because the receptor's ligand binding domain sequence is conserved between mouse and rat species, the receptor is denoted...
| Keywords: | Nr1c3, Pparg, PPAR-gamma, Nuclear receptor subfamily 1 group C member 3, Peroxisome proliferator-activated receptor gamma |
| Application: | Functional activity screening |
| Species reactivity: | mouse, rat |
From 1,448.00€
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PPARgamma (human) Reporter Assay Kit
Item number: IB-IB00102
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor gamma (NR1C3), a ligand-dependent transcription factor commonly referred to as PPARG or PPARgamma. INDIGO's reporter cells include...
| Keywords: | NR1C3, PPARG, PPAR-gamma, Nuclear receptor subfamily 1 group C member 3, Peroxisome proliferator-activated receptor gamma |
| Application: | Functional activity screening |
| Species reactivity: | human |
3,802.00€
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PPARalpha (human) Reporter Assay Kit
Item number: IB-IB00112
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor alpha (NR1C1), a ligand-dependent transcription factor commonly referred to as PPARA or PPARalpha. INDIGO's reporter cells include...
| Keywords: | NR1C1, PPARA, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1, Peroxisome proliferator-activated receptor alpha |
| Application: | Functional activity screening |
| Species reactivity: | human |
3,802.00€
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PPARdelta (human) Reporter Assay Kit
Item number: IB-IB00122
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor delta (NR1C2), a ligand-dependent transcription factor commonly referred to as PPARD or PPARdelta. INDIGO's reporter cells include...
| Keywords: | NUCI, NUC1, NR1C2, PPARD, PPAR-beta, PPAR-delta, Nuclear hormone receptor 1, Nuclear receptor subfamily 1 group C member... |
| Application: | Functional activity screening |
| Species reactivity: | human |
3,802.00€
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LXR (human) Reporter Assays Panel
Item number: IB-IB00321-48P
INDIGO's panel of LXR Assays utilizes non-human mammalian cells engineered to express human estrogen receptors alpha (NR1H3) and beta (NR1H2), ligand-dependent transcription factors commonly referred to as LXRalpha and LXRbeta. INDIGO's reporter cells include the luciferase reporter gene functionally linked to an...
| Application: | Functional activity screening |
| Species reactivity: | human |
1,894.00€
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ERbeta (human) Reporter Assay Kit
Item number: IB-IB00412
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the full-length human estrogen receptor 2 (NR3A2), a ligand-dependent transcription factor commonly referred to as ERbeta. INDIGO's reporter cells include the luciferase reporter gene...
| Keywords: | ESR2, ESTRB, ER-beta, Estrogen receptor beta, Nuclear receptor subfamily 3 group A member 2 |
| Application: | Functional activity screening |
| Species reactivity: | human |
3,802.00€
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ER (human) Reporter Assays Panel
Item number: IB-IB00421-48P
INDIGO's panel of ER assays utilizes non-human mammalian cells engineered to express human estrogen receptors alpha (ER1, NR3A1) and beta (ER2, NR3A2), ligand-dependent transcription factors commonly referred to as ERalpha and ERbeta. INDIGO's ER reporter cells include the luciferase reporter gene functionally...
| Keywords: | estrogen receptor alpha, ER1, NR3A1, estrogen receptor beta, ER2, NR3A2 |
| Application: | Functional activity screening |
| Species reactivity: | human |
1,894.00€
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VDR (human) Reporter Assay Kit
Item number: IB-IB00702
This nuclear receptor assay system utilizes proprietary human cells engineered to provide constitutive, high-level expression of the human vitamin D receptor (NR1I1), a ligand-dependent transcription factor commonly referred to as VDR. INDIGO's reporter cells include the luciferase reporter gene functionally linked...
| Keywords: | VDR, NR1I1, Vitamin D3 receptor, 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1 |
| Application: | Functional activity screening |
| Species reactivity: | human |
3,802.00€
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