Products from Indigo Biosciences
Indigo Biosciences, Inc. was founded in 2005 in State College, Pennsylvania by Dr. Jack Vanden Heuvel and Dr. Blake Peterson. It remains a privately held biosciences company offering products and services focused on in vitro toxicology and nuclear receptors. These receptors comprise a major class of therapeutic drug targets. The company’s founders leveraged their collective expertise in nuclear receptor biology, toxicology, medical chemistry and molecular biology to establish the core platform technology of the company.
More information at: www.indigobiosciences.com
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MR Reporter Assay System (Mouse)
Item number: IB-M00501
This Mouse Mineralocorticoid Receptor (MR) assay kit is an all-inclusive mouse MR reporter assay system that includes, in addition to mouse MR Reporter Cells, two optimized media for use during cell culture and (optionally) in diluting the test samples, a reference agonist, Luciferase Detection Reagent, a cell...
| Keywords: | MR, Mlr, Nr3c2, Mineralocorticoid receptor, Nuclear receptor subfamily 3 group C member 2 |
| Application: | Functional activity screening |
| Species reactivity: | mouse |
1,448.00€
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ERbeta (human) Reporter Assay Kit
Item number: IB-IB00411
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the full-length human estrogen receptor 2 (NR3A2), a ligand-dependent transcription factor commonly referred to as ERbeta. INDIGO's reporter cells include the luciferase reporter gene...
| Keywords: | ESR2, ESTRB, ER-beta, Estrogen receptor beta, Nuclear receptor subfamily 3 group A member 2 |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,448.00€
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RARbeta (human) Reporter Assay Kit
Item number: IB-IB02101
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoic acid receptor, beta (NR1B2), a ligand-dependent transcription factor commonly referred to as RARB or RARbeta. INDIGO's reporter cells include the luciferase reporter...
| Keywords: | HAP, RARB, RAR-beta, RAR-epsilon, HBV-activated protein, Retinoic acid receptor beta, Nuclear receptor subfamily 1 group B... |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,448.00€
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PXR (human) Reporter Assay Kit
Item number: IB-IB07001
Protein function: Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the...
| Keywords: | SXR, PXR, NR1I2, Pregnane X receptor, Orphan nuclear receptor PXR, Orphan nuclear receptor PAR1, Steroid and xenobiotic... |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,448.00€
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RARalpha (human) Reporter Assay Kit
Item number: IB-IB02201
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoic acid receptor, alpha (NR1B1), a ligand-dependent transcription factor commonly referred to as RARA or RARalpha. INDIGO's reporter cells include the luciferase...
| Keywords: | RARA, NR1B1, RAR-alpha, Retinoic acid receptor alpha, Nuclear receptor subfamily 1 group B member 1 |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,448.00€
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RORa (Human) Reporter Assay System
Item number: IB-IB04011
Protein function: Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of embryonic development, cellular differentiation, immunity, circadian rhythm as well as lipid, steroid,...
| Keywords: | RORA, NR1F1, Nuclear receptor ROR-alpha, Nuclear receptor RZR-alpha, RAR-related orphan receptor A, Retinoid-related... |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,448.00€
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RARgamma (human) Reporter Assay Kit
Item number: IB-IB02001
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoic acid receptor gamma (NR1B3), a ligand-dependent transcription factor commonly referred to as RARG or RARgamma. INDIGO's reporter cells include the luciferase...
| Keywords: | RARG, NR1B3, RAR-gamma, Retinoic acid receptor gamma, Nuclear receptor subfamily 1 group B member 3 |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,448.00€
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RXRbeta (human) Reporter Assay Kit
Item number: IB-IB00811
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor beta (NR2B2), a ligand-dependent transcription factor commonly referred to as RXRB or RXRbeta. INDIGO's reporter cells include the luciferase reporter...
| Keywords: | RXRB, NR2B2, Retinoid X receptor beta, Retinoic acid receptor RXR-beta, Nuclear receptor subfamily 2 group B member 2 |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,448.00€
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RXRgamma (human) Reporter Assay Kit
Item number: IB-IB00821
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor gamma (NR2B3), a ligand-dependent transcription factor commonly referred to as RXRG or RXRgamma. INDIGO's reporter cells include the luciferase reporter...
| Keywords: | RXRG, NR2B3, Retinoid X receptor gamma, Retinoic acid receptor RXR-gamma, Nuclear receptor subfamily 2 group B member 3 |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,448.00€
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RXRalpha (human) Reporter Assay Kit
Item number: IB-IB00801
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor alpha (NR2B1), a ligand-dependent transcription factor commonly referred to as RXRA or RXRalpha. INDIGO's reporter cells include the luciferase reporter...
| Keywords: | RXRA, NR2B1, Retinoid X receptor alpha, Retinoic acid receptor RXR-alpha, Nuclear receptor subfamily 2 group B member 1 |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,448.00€
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PPAR (human) Reporter Assays Panel
Item number: IB-IB00131-32P
INDIGO's panel of PPAR reporter assays utilizes non-human mammalian cells engineered to express human peroxisome proliferator-activated receptors: PPARalpha (NR1C1), PPARdelta (NR1C2), or PPARgamma (NR1C3), all ligand-dependent transcription factors that are commonly referred to as PPARalpha, PPARdelta and...
| Keywords: | PPARalpha (NR1C1), PPARdelta (NR1C2), PPARgamma (NR1C3) |
| Application: | Functional activity screening |
| Species reactivity: | human |
1,894.00€
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LXRbeta (human) Reporter Assay Kit
Item number: IB-IB00302
This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of human liver X receptor beta (NR1H2), a ligand-dependent transcription factor commonly referred to as LXRbeta. INDIGO's reporter cells include the luciferase reporter gene...
| Keywords: | LXRB, NR1H2, Nuclear receptor NER, Liver X receptor beta, Oxysterols receptor LXR-beta, Ubiquitously-expressed nuclear... |
| Application: | Functional activity screening |
| Species reactivity: | human |
3,802.00€
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