Products from Indigo Biosciences
Indigo Biosciences, Inc. was founded in 2005 in State College, Pennsylvania by Dr. Jack Vanden Heuvel and Dr. Blake Peterson. It remains a privately held biosciences company offering products and services focused on in vitro toxicology and nuclear receptors. These receptors comprise a major class of therapeutic drug targets. The company’s founders leveraged their collective expertise in nuclear receptor biology, toxicology, medical chemistry and molecular biology to establish the core platform technology of the company.
More information at: www.indigobiosciences.com
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PPARgamma (human) Reporter Assay Kit
Item number: IB-IB00101
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor gamma (NR1C3), a ligand-dependent transcription factor commonly referred to as PPARG or PPARgamma. INDIGO's reporter cells include...
| Keywords: | NR1C3, PPARG, PPAR-gamma, Nuclear receptor subfamily 1 group C member 3, Peroxisome proliferator-activated receptor gamma |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,448.00€
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ERalpha (human) Reporter Assay Kit
Item number: IB-IB00401
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the full-length human estrogen receptor 1 (NR3A1), a ligand-dependent transcription factor commonly referred to as ERalpha. INDIGO's reporter cells include the luciferase reporter gene...
| Keywords: | ER, ESR, ESR1, ER-alpha, Estrogen receptor, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1 |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,448.00€
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Nrf2 (Human) Reporter Assay System
Item number: IB-IB10001
Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating...
| Keywords: | NRF2, HEBP1, NFE2L2, NFE2-related factor 2, NF-E2-related factor 2, Nuclear factor erythroid 2-related factor 2, Nuclear... |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,448.00€
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PPARalpha (human) Reporter Assay Kit
Item number: IB-IB00111
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor alpha (NR1C1), a ligand-dependent transcription factor commonly referred to as PPARA or PPARalpha. INDIGO's reporter cells include...
| Keywords: | NR1C1, PPARA, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1, Peroxisome proliferator-activated receptor alpha |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,448.00€
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FXR (human) Reporter Assay Kit
Item number: IB-IB00601-32
This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of human farnesoid X receptor (NR1H4), a ligand-dependent transcription factor commonly referred to as FXR. INDIGO's reporter cells include the luciferase reporter gene...
| Keywords: | BAR, NR1H4, Bile acid receptor, Farnesol receptor HRR-1, RXR-interacting protein 14, Farnesoid X-activated receptor,... |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,448.00€
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GR Bioassay for Environmental Sample Monitoring
Item number: IB-EM00201
This Glucocorticoid Receptor Bioassay for Environmental Sample Monitoring kit is an all-inclusive luciferase reporter assay system that includes, in addition to ER Reporter Cells, two optimized media for use during cell culture and in diluting the user's test samples, the reference agonist Dexamethasone, Luciferase...
| Keywords: | GR, GRL, NR3C1, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1 |
| Application: | Functional activity screening |
| Species reactivity: | human |
1,448.00€
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ER Bioassay for Environmental Sample Monitoring
Item number: IB-EM00431
This Estrogen Receptor Bioassay for Environmental Sample Monitoring kit is an all-inclusive luciferase reporter assay system that includes, in addition to ER Reporter Cells, two optimized media for use during cell culture and in diluting the user's test samples, the reference agonist 17beta-estradiol (E2),...
| Keywords: | ER, ESR, ESR1, ER-alpha, Estrogen receptor, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1 |
| Application: | Functional activity screening |
| Species reactivity: | human |
1,448.00€
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MR Bioassay for Environmental Sample Monitoring
Item number: IB-EM00501
This Mineralocorticoid Receptor Bioassay for Environmental Sample Monitoring kit is an all-inclusive luciferase reporter assay system that includes, in addition to MR Reporter Cells, two optimized media for use during cell culture and in diluting the user's test samples, the reference agonist Aldosterone, Luciferase...
| Keywords: | MR, MCR, NR3C2, Mineralocorticoid receptor, Nuclear receptor subfamily 3 group C member 2 |
| Application: | Functional activity screening |
| Species reactivity: | human |
1,448.00€
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AR Bioassay for Environmental Sample Monitoring
Item number: IB-EM03001
This Androgen Receptor Bioassay for Environmental Sample Monitoring kit is an all-inclusive luciferase reporter assay system that includes, in addition to AR Reporter Cells, two optimized media for use during cell culture and in diluting the user's test samples, Luciferase Detection Reagent, and a cell culture-ready...
| Keywords: | AR, DHTR, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4 |
| Application: | Functional activity screening |
| Species reactivity: | human |
1,448.00€
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AhR Bioassay for Environmental Sample Monitoring
Item number: IB-EM06001
This Aryl Hydrocarbon Receptor Bioassay for Environmental Sample Monitoring kit is an all-inclusive luciferase reporter assay system that includes, in addition to AhR Reporter Cells, this kit includes are two optimized media for use during cell culture and in diluting the user's test samples, Luciferase Detection...
| Keywords: | AhR, bHLHe76, Ah receptor, Aryl hydrocarbon receptor, Class E basic helix-loop-helix protein 76 |
| Application: | Functional activity screening |
| Species reactivity: | human |
1,448.00€
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GM-CSFR Reporter Assay System (Human)
Item number: IB-IB30001
This Granulocyte-Macrophage Colony-Stimulating Factor Receptor (GM-CSFR) assay kit is an all-inclusive luciferase reporter assay system that includes, in addition to GM-CSFR Reporter Cells, optimized culture medium for use in reviving the cryopreserved cells, a culture medium for use in preparing test sample...
| Keywords: | CD116, CSF2R, CDw116, CSF2RA, GMR-alpha, GMCSFR-alpha, GM-CSF-R-alpha, Granulocyte-macrophage colony-stimulating factor... |
| Application: | Functional activity screening |
| Species reactivity: | human |
1,448.00€
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GM-CSFR Reporter Assay System (Human)
Item number: IB-IB30002
This Granulocyte-Macrophage Colony-Stimulating Factor Receptor (GM-CSFR) assay kit is an all-inclusive luciferase reporter assay system that includes, in addition to GM-CSFR Reporter Cells, optimized culture medium for use in reviving the cryopreserved cells, a culture medium for use in preparing test sample...
| Keywords: | CD116, CSF2R, CDw116, CSF2RA, GMR-alpha, GMCSFR-alpha, GM-CSF-R-alpha, Granulocyte-macrophage colony-stimulating factor... |
| Application: | Functional activity screening |
| Species reactivity: | human |
3,802.00€
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