Products from Chimerigen Laboratories
Chimerigen develops and manufactures unique, immunoglobulin-based, chimeric fusion proteins and related research products using advanced cellular and molecular biological techniques. These reagents are used successfully in basic biomedical and applied research.
More information at: www.adipogen.com/chimerigen
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Semaphorin-4A (mouse):Fc (human) (rec.)
Item number: CHI-MF-111SEMA4-C100
The extracellular domain of mouse Semaphorin-4A (aa 1-676) is fused at the C-terminus to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Semaphorin 4A (Sema4A, previously semB) is a Class 4 transmembrane Semaphorin with activity in the immune and nervous systems. Sema4A was first...
| Keywords: | Semab, Sema4a, Sema B, Semaphorin-B, Semaphorin-4A |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | mouse |
512.00€
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CD274 [B7-H1/PD-L1] (mouse):Fc (mouse) (rec.) (non-lytic)
Item number: CHI-MF-120PDL1-C100
The extracellular domain of mouse CD274 [B7-H1] (aa 19-237) is fused to the N-terminus of the Fc region of a mutant mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the CD274 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Programmed...
| Keywords: | B7h1, B7-H1, Cd274, PD-L1, CD274, B7 homolog 1, PDCD1 ligand 1, Programmed death ligand 1, Programmed cell death 1 ligand 1 |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | mouse |
429.00€
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SCF (mouse):Fc (mouse) (rec.) (non-lytic)
Item number: CHI-MF-120SCF-C050
The extracellular domain of mouse SCF (aa 26-214) is fused at the C-terminus to the Fc portion of a mutant mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the SCF moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Stem cell factor...
| Keywords: | MGF, SCF, Kitl, Kitlg, sKITLG, Kit ligand, c-Kit ligand, Steel factor, Stem cell factor, Soluble KIT ligand, Mast cell... |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | mouse |
314.00€
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HMGB1 (rat) (rec.) (His)
Item number: CHI-RR-300HMGB1-C025
HMGB1 was originally discovered as an essential DNA-binding protein for regulating p53, NF-kappaB and other important proteins. It is secreted from activated dentric cells, macrophage and nectrotic cells, and acts as a ligand for RAGE, TLR-2 and TLR-4 expressed on surrounding cells. As a result, HMGB1 activates Rac,...
| Keywords: | HMG-1, Hmgb1, Amphoterin, Heparin-binding protein p30, High mobility group protein 1, High mobility group protein B1 |
| Application: | Bioassays |
| Expressed in: | E.coli |
| Origin: | rat |
341.00€
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IL-22 (human):Fc (human) (rec.)
Item number: CHI-HF-21022-C025
The extracellular domain of human IL-22 (aa 34-179) is fused at the C-terminus to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin-22 (IL-22), also known as IL-10 related T cell derived inducible factor (ILTIF) was initially identified as a gene induced by IL-9 in mouse T...
| Keywords: | IL22, IL-22, ILTIF, IL-TIF, Interleukin-22, Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | human |
314.00€
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IFN-gamma (human) (rec.) (His)
Item number: CHI-HR-200IFNG-C010
IFN gamma, also known as IFNG, is a secreted protein which belongs to the type I I interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity...
| Keywords: | IFNG, IFN-gamma, Interferon gamma, Immune interferon, Interferon-gamma IFNG |
| Application: | Bioassays |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | ~17 kD |
From 132.00€
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IL-8 (human):Fc (human) (rec.) (nonlytic)
Item number: CHI-HF-22008-C050
Unfortunately, most cytokines have short circulating half-lives. With the creation of a group of new immunoglobulin- based cytokine fusion proteins, in which a cytokine sequence had been genetically fused to the hinge, CH2 and CH3 regions of an immunoglobulin, these cytokine fusion proteins possess both the...
| Keywords: | Interleukin-8, CXCL8, C-X-C Motif Chemokine 8, Emoctakin, GCP-1, LAI, MDNCF, MONAP, NAP-1, NCF, TCF |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | human |
From 171.00€
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Interleukin-4, human recombinant (rHuIL-4) (His)
Item number: CHI-HR-20004-C010
Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts...
| Keywords: | BCGF, BCDF, B cell stimulating factor, BSF-1, Lymphocyte stimulatory factor 1, IL-4, MGC79402, Binetrakin, Pitrakinra |
| Application: | Bioassays |
| Expressed in: | E.coli |
| Origin: | human |
226.00€
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COVID-19 Research
SARS-CoV-2 Nucleocapsid Protein (rec.) (His)
Item number: CHI-B233501-C100
Accession Number: QHD43423.2. SARS-CoV-2 Nucleocapsid protein (aa 1-419) is fused at the N-terminus to a His-tag. Endotoxin Content: <1EU/µg purified protein (LAL test). SARS-CoV-2 shares 79.5% sequence identity with SARS-CoV and is 96.2% identical at the genome level to the bat coronavirus BatCoV RaTG133,...
| Keywords: | 2019-nCoV N Protein |
| Expressed in: | E.coli |
| Origin: | SARS-CoV-2 |
341.00€
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GITRL, Soluble (human) (rec.)
Item number: CHI-AG-40A-0019-C050
GITRL (Glucocorticoid-induced TNF receptor ligand) is expressed on dendritic cells (DC), monocytes, macrophages, B cells, activated T cells, endothelial cells, osteoclasts and various healthy non-lymphoid tissues (e.g. testis). GITRL is constitutively expressed and released as soluble form by solid tumors and...
| Keywords: | AITRL, hGITRL, TNFSF18, Activation-inducible TNF-related ligand, Glucocorticoid-induced TNF-related ligand, Tumor necrosis... |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | ~17 kD |
468.00€
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IL-17A (human):Fc (human) (rec.)
Item number: CHI-AG-40A-0066-C050
Interleukin-17A (IL-17A) exhibits multiple biological activities on a variety of cells including the induction of IL-6 and IL-8 production in fibroblasts, the enhancement of surface expression of ICAM-1 in fibroblasts, activation of NF-kappaB and costimulation of T cell proliferation. Induces stromal cells to...
| Keywords: | IL17A, IL-17, CTLA8, IL-17A, CTLA-8, Interleukin-17A, Cytotoxic T-lymphocyte-associated antigen 8 |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | ~42 kD |
495.00€
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CD276 [B7-H3] (human) (rec.)
Item number: CHI-HF-200B7H3-C050
CD276 (B7-H3) is a member of the B7/CD28 superfamily of costimulatory molecules serving as an accessory modulator of T cell response. B7 family molecules, which are expressed on antigen-presenting cells and display extracellular regions containing immunoglobulin (Ig) variable (V)- and constant (C)-like domains, are...
| Keywords: | B7H3, CD276, B7-H3, PSEC0249, 4Ig-B7-H3, B7 homolog 3, CD276 antigen, Costimulatory molecule, B7-H3 |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | ~35 kD |
391.00€
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