Products from BPS Bioscience
BPS Bioscience Inc., headquartered in the heart of one of the world's largest clusters of life science research institutes and companies in San Diego, California, is the leading provider of highest quality HDACs, histone demethylases and methyltransferases, ubiquitin pathway proteins, phosphodiesterases, kinases, phosphatases, and other recombinant enzymes. BPS also provides custom protein development, recombinant cell lines, biochemical and cell-based assays as well as compound screening services to accelerate your drug discovery research. Recently, the portfolio was also expanded to include various virus-based tools.
More information at: www.bpsbioscience.com
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HCV2a, FLAG-His-tags Recombinant
Item number: BPS-80108
Hepatitis C virus (HCV) genotype 2a, also known as HCV2a, is a fusion protein of a.a. 21-32 of NS4A, linker (4 a.a.) and a.a. 3-181 of NS3 (GenBank Accession No. FJ393024) with N-terminal FLAG-His-tag, MW = 22.3 kDa, expressed in an E. coli expression system.
| Keywords: | Genome polyprotein, |
| Application: | Enzyme assays |
| Expressed in: | E.coli |
| Origin: | HCV |
| MW: | 22,3 kD |
613.00€
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HCV1b (R155K), FLAG-His-tags Recombinant
Item number: BPS-80109
Fusion protein corresponding to the serine protease NS3 (a.a. 3-181) and cofactor NS4A (a.a. 21-32) from Hepatitis C virus genotype 1b (GenBank Accession No. AF054247) with Arg-to-Lys mutation on a.a. 155, an N-terminal FLAG-His tag, and a 4 a.a. linker, MW = 22.3 kDa, expressed in an E. coli expression system.
| Keywords: | hepatitis c virus genotype 1b K155, |
| Application: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Expressed in: | E.coli |
| Origin: | HCV |
| MW: | 22,3 kD |
613.00€
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HCV1b (D168V), FLAG-His-tags Recombinant
Item number: BPS-80110
Hepatitis C virus (HCV) genotype 1b, also known as HCV1b, is a fusion protein of a.a. 21-32 of NS4A, linker (4 a.a.) and a.a. 3-181 of NS3 (GenBank Accession No. AF054247) with Asp-to-Val mutation on a.a. 168, and N-terminal FLAG-His-tag, MW = 22.3 kDa, expressed in an E. coli expression system.
| Keywords: | hepatitis c virus genotype 1b V168, |
| Application: | Protease |
| Expressed in: | E.coli |
| Origin: | HCV |
| MW: | 22,3 kD |
613.00€
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MDM2-Driven p53 Ubiquitination Assay Kit
Item number: BPS-82179
The MDM2-Driven p53 Ubiquitination Assay kit is a sensitive AlphaLisa(R) high-throughput screening (HTS) assay designed to measure MDM2 (mouse double minute 2 homolog) E3 ligase activity in a homogeneous 384 reaction format. The assay kit comes with enough biotinylated ubiquitin, ATP, FLAG-tagged p53, assay buffer,...
| Keywords: | Hdm2, MDM2, Oncoprotein Mdm2, Double minute 2 protein, p53-binding protein Mdm2, E3 ubiquitin-protein ligase Mdm2,... |
| Application: | Inhibitor screening, drug discovery, HTS, IC50 determination, MDM2-driven ubiquitination studies |
| Species reactivity: | human |
2,518.00€
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Chemi-Verse(TM) PAK4 Kinase Assay Kit
Item number: BPS-82181
The Chemi-Verse(TM) PAK4 Kinase Assay Kit is designed to measure PAK4 (p21-activated kinase 4) serine/threonine kinase activity for screening and profiling applications using ADP-Glo(TM) as a detection reagent. The assay kit comes in a convenient 96-well format, with enough purified recombinant PAK4 kinase, kinase...
| Keywords: | PAK4, PAK-4, KIAA1142, EC=2.7.11.1, p21-activated kinase 4, Serine/threonine-protein kinase PAK 4, |
| Application: | Enzyme kinetics, screen small molecule inhibitor screening, drug discovery, HTS |
| Species reactivity: | human |
789.00€
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Chemi-Verse(TM) PAK6 Kinase Assay Kit
Item number: BPS-82182
The Chemi-Verse(TM) PAK6 Kinase Assay Kit is designed to measure PAK6 (p21-activated kinase 6) serine/threonine kinase activity for screening and profiling applications using ADP-Glo(TM) as a detection reagent. The assay kit comes in a convenient 96-well format, with enough purified recombinant PAK6 kinase, kinase...
| Keywords: | PAK6, PAK5, PAK-6, PAK-5, EC=2.7.11.1, p21-activated kinase 6, Serine/threonine-protein kinase PAK 6, |
| Application: | Enzyme kinetics, screen small molecule inhibitor screening, drug discovery, HTS |
| Species reactivity: | human |
789.00€
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Chemi-Verse(TM) PAK7 Kinase Assay Kit
Item number: BPS-82183
The Chemi-Verse(TM) PAK7 Kinase Assay Kit is designed to measure PAK7 (p21-activated kinase 7) serine/threonine kinase activity for screening and profiling applications using ADP-Glo(TM) as a detection reagent. The assay kit comes in a convenient 96-well format, with enough purified recombinant PAK7 kinase, kinase...
| Keywords: | PAK-7, PAK-5, KIAA1264, EC=2.7.11.1, p21-activated kinase 5, p21-activated kinase 7, Serine/threonine-protein kinase PAK 5, |
| Application: | Enzyme kinetics, screen small molecule inhibitor screening, drug discovery, HTS |
| Species reactivity: | human |
789.00€
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Costunolide
Item number: BPS-27745-2
Costunolide is a sesquiterpene lactone with anti-oxidant properties that is found in lettuce and other plants. It is widely used in many herbal medicines. Costunolide is a potent inducer of apoptosis, a potent anti-cancer agent, has anti-inflammatory, anti-viral, anti-fungal, antimycobacterial activity and has been...
| Keywords: | (+)-Costunolide, Costunolid, Costus lactone, NSC 106404, |
| Application: | Apoptosis inhibitor, anticancer agent |
| MW: | 232.3 D |
350.00€
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CBL-B TR-FRET Assay Kit
Item number: BPS-79575
Human Casitas B-lineage lymphoma proto-oncogene b (CBL-B) is an E3 ubiquitinprotein ligase that functions as a negative regulator of T-cell activation. It is a promising drug target in cancer immunotherapy. The CBL-B TR-FRET Assay Kit is designed to measure CBL-B auto-ubiquitination activity in a homogeneous 384...
| Keywords: | UBE1, UBA1, ubcH5b, UBE2D2, E3 ubiquitin-protein ligase CBL-B, RING finger protein 56, CBL, CBLB, HTRF, cblb, |
| Application: | Drug discovery, HTS |
| Species reactivity: | human |
3,138.00€
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LysA(TM) Universal PARylation Assay Kit
Item number: BPS-82123
LysA(TM) Universal PARylation Assay Kit is a sandwich ELISA-based kit designed to measure and quantify the amount of total poly ADP-ribosylation present in cell extracts. The kit comes in a convenient 96-well format and contains all the reagents needed, including a PAR standard that allows to establish a standard...
| Keywords: | poly-ADP-ribosylation |
| Application: | Poly-ADP-ribosylation quantification, PARP/PARG inhibitor screening/IC50 determination/validation |
1,603.00€
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ACC-1, active human recombinant protein
Item number: BPS-50202
Human ACC1 (acetyl-Coenzyme A carboxylase alpha transcript variant 1) (GenBank Accession No. NM_198834), amino acids 1-2383(end) with C-terminal FLAG and His-tags, MW = 270 kDa, expressed in Baculovirus infected Sf9 cell expression system. A 25 µl ACC1 reaction is conducted in a buffer containing 30 mM HEPES (pH...
| Keywords: | ACAC, ACC1, ACC-alpha, Acetyl-CoA carboxylase 1, Acetyl-Coenzyme A carboxylase alpha, |
| Application: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Expressed in: | Baculovirus |
| Origin: | human |
| MW: | 271 kD |
898.00€
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IDH1(R132H) Assay Kit
Item number: BPS-79376
The IDH1(R132H) Assay Kit is designed to measure IDH1(R132H) activity for screening and profiling applications by measuring NADPH consumption.
| Keywords: | Isocitrate Dehydrogenase 1, IDH1, Oxalosuccinate Decarboxylase, IDHM, |
| Application: | Drug discovery, HTS |
| Species reactivity: | human |
789.00€
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