Products from AdipoGen Life Sciences
AdipoGen Life Sciences is a manufacturer of reagents for immunometabolism & advanced inflammation research. The headquarters are located in San Diego, USA with a manufacturing laboratory in Switzerland. A motivated team of highly skilled researchers develops new products for the Life Science Reagents Market in the areas cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cells and neurodegeneration. The major focus is on innovative and advanced ELISA-Kits. In addition to the antibody and protein facilities, AdipoGen also owns chemical laboratories, enabling the company to develop new and innovative biochemicals.
More information at: www.adipogen.com
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AOH1996
Item number: AG-CR1-3553-M005
AOH1996 is an orally available and metabolically stable small molecule PCNA inhibitor, which selectively kills cancer cells, with a median concentration of about 300 nM for 50% growth inhibition. AOH1996 was not significantly toxic to non-malignant cells, even up to 10 µM. AOH1996 enhances the interaction between...
| Keywords: | NSC789796, N-(2-((2-(3-Methoxyphenoxy)phenyl)amino)-2-oxoethyl)-1-naphthamide |
| CAS | 2089314-64-5 |
| MW: | 426.5 D |
From 132.00€
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Nigericin, sodium salt
Item number: AG-CN2-0020-M005
Isolated from Streptomyces hygroscopicus. Antibiotic. High affinity ionophore for monovalent cations such as H, K, Na, Pb2. Shows antibacterial (Gram-positive), antifungal, antitumor and antiviral activity. Disrupts membrane potential and Golgi apparatus in mitochondria. NLRP3/NALP3 activator. Signals through...
| Keywords: | Antibiotic K 178, Helexin C, Polyetherin A, BRN 1696755, Azalomycin M, Antibiotic X-464 |
| Application: | Ionophore |
| CAS | 28643-80-3 |
From 66.00€
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YM-254890
Item number: AG-CN2-0509-MC05
Off-white solid. Soluble in DMSO (10mg/ml). Cyclic depsipeptide composed of unique amino acids differing from normal amino acids, Membrane permeable, potent and selective Galphaq family inhibitor, Inhibits the signal transduction of Galphaq, Galpha11 and Galpha14 (IC50=0.095&mu,M) by blocking the exchange of GDP for...
| Keywords: | QS 3666A |
| Application: | G alpha q family inhibitor |
| CAS | 568580-02-9 |
| MW: | 960,1 D |
From 220.00€
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Fc (LALA-PG)-KIH (human) IgG1 Control (rec.)
Item number: AG-35B-0018-C050
Negative control in experiments with recombinant proteins fused to human IgG1 Fc (LALA-PG)-KIH (Knobs-into-Holes) (e.g. Prod. No. AG-40B-0248). This protein is not an appropriate negative control for other standard Fc protein constructs. The protein Fc (LALA-PG)-KIH (human) IgG1 Control (rec.) is produced by using...
| Keywords: | Ig gamma-1 chain C region, Ig gamma-1 chain C region EU, Ig gamma-1 chain C region NIE, Ig gamma-1 chain C region KOL,... |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 28 kD |
341.00€
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IL-38 (human) (rec.) (His)
Item number: AG-40A-0191Y-3010
IL-38 (IL-1F10) mRNA is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-1F10 in the inflammatory response. It has been reported that removal of the N-terminus domain of the interleukins of the IL-1F...
| Keywords: | FIL1T, IL-38, FKSG75, IL-1HY2, IL-1F10, IL-1 theta, FIL1 theta, Interleukin-38, Interleukin-1 HY2, Interleukin-1 theta,... |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 18 kD |
From 264.00€
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Fc (LALA-PG)-KIH (human):GDF15 (mouse) (rec.)
Item number: AG-40B-0245-C050
Growth and differentiation factor 15 (GDF15, also known as macrophage inhibitory cytokine-1 (MIC-1)), is a member of the transforming growth factor (TGF)-beta superfamily and was initially identified in activated macrophages. GDF15 acts through a recently identified receptor called Glial-derived Neurotrophic Factor...
| Keywords: | MIC-1, GDF-15, Growth/differentiation factor 15, Macrophage inhibitory cytokine 1 |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 4530 kD |
440.00€
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Fc (LALA-PG)-KIH (human):Irisin (monomeric) (rec.)
Item number: AG-40B-0246-C050
Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the...
| Keywords: | FNDC5, FRCP2 |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 5530 kD |
440.00€
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IL-23 (mouse):Fc (LALA-PG)-KIH (human) (rec.)
Item number: AG-40B-0248-C050
Interleukin-12 (IL-12) family members are heterodimer glycoproteins, composed of two covalently linked subunits, alpha and beta chains. The alpha-subunit consists of IL-23p19, IL-27p28, and IL-12p35, and the beta-subunit includes IL-12p40 and Epstein-Barr virus-induced gene (Ebi3). IL-12 members bind to cognate...
| Keywords: | Il23a, IL-23-A, IL-23p19, IL-23 subunit alpha, Interleukin-23 subunit p19, Interleukin-23 subunit alpha |
| Expressed in: | Hamster cells |
| Origin: | mouse |
| MW: | 7555 kD |
440.00€
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IL-27 (mouse):Fc (LALA-PG)-KIH (human) (rec.)
Item number: AG-40B-0249-C050
Interleukin-12 (IL-12) family members are heterodimer glycoproteins, composed of two covalently linked subunits, alpha and beta chains. The alpha-subunit consists of IL-23p19, IL-27p28, and IL-12p35, and the beta-subunit includes IL-12p40 and Epstein-Barr virus-induced gene (Ebi3). IL-12 members bind to cognate...
| Keywords: | p28, Il27, Il27a, IL27-A, IL-27-A, IL-27 subunit alpha, Interleukin-27 subunit alpha |
| Expressed in: | Hamster cells |
| Origin: | mouse |
| MW: | 6260 kD |
440.00€
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Isthmin-1 (human) ELISA Kit
Item number: AG-45B-0032-KI01
Isthmin-1 (ISM1) was first identified as a gene expressed in the Xenopus midbrain-hindbrain organizer called the isthmus, with a proposed role during early brain development. Isthmin-1 encodes a predicted ~50-kDa protein containing a signal peptide, a thrombospondin domain and an adhesion-associated domain....
| Keywords: | ISM1, C20orf82, Isthmin-1 |
| Application: | ELISA |
| Species reactivity: | human |
550.00€
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Spilanthol
Item number: AG-CN2-0543-M005
Spilanthol is a natural non-toxic compound. It is a sesquiterpene lactone and has been traditionally used in folk medicine. It has sensory properties (pungency, tingling, numbing, mouth-watering) and is an excellent stable model compound for sensory/chemoreception studies like pellitorine and a biological analog of...
| Keywords: | Affinin, (2E,6Z,8E)-N-Isobutyldeca-2,6,8-trienamide |
| CAS | 25394-57-4 |
| MW: | 221,3 D |
297.00€
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Inosine
Item number: AG-CR1-3554-G001
Inosine, an intermediate in purine metabolism, consists of hypoxanthine and ribose. It is an inert purine nucleoside formed by breakdown of adenosine (deamination, known as A-to-I editing that occurs in tRNA and mRNA) or also is generated by the action of 5'-nucleotidase on inosine monophosphate (IMP). Inosine has...
| Keywords: | 9-beta-D-Ribofuranosylhypoxanthine, NSC 20262, Hypoxanthine 9-beta-D-ribofuranoside |
| CAS | 58-63-9 |
| MW: | 268,2 D |
From 22.00€
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