Products from AdipoGen Life Sciences
AdipoGen Life Sciences is a manufacturer of reagents for immunometabolism & advanced inflammation research. The headquarters are located in San Diego, USA with a manufacturing laboratory in Switzerland. A motivated team of highly skilled researchers develops new products for the Life Science Reagents Market in the areas cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cells and neurodegeneration. The major focus is on innovative and advanced ELISA-Kits. In addition to the antibody and protein facilities, AdipoGen also owns chemical laboratories, enabling the company to develop new and innovative biochemicals.
More information at: www.adipogen.com
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YM-254890
Item number: AG-CN2-0509-MC05
Off-white solid. Soluble in DMSO (10mg/ml). Cyclic depsipeptide composed of unique amino acids differing from normal amino acids, Membrane permeable, potent and selective Galphaq family inhibitor, Inhibits the signal transduction of Galphaq, Galpha11 and Galpha14 (IC50=0.095&mu,M) by blocking the exchange of GDP for...
| Keywords: | QS 3666A |
| Application: | G alpha q family inhibitor |
| CAS | 568580-02-9 |
| MW: | 960,1 D |
From 220.00€
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Ganglioside GM1 . sodium salt (bovine brain)
Item number: AG-CN2-9000-M001
Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell...
| Keywords: | GM1 . Na, Monosialoganglioside GM1 . Na |
| Application: | Acidic glycosphingolipid |
| CAS | 37758-47-7 |
| MW: | 1545,8 D |
From 99.00€
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Forskolin
Item number: AG-CN2-0089-M050
Isolated from Coleus forskohlii. Potent, cell permeable adenylyl cyclase activator. Increases intracellular cAMP levels. Widely used tool to investigate cAMP as a second messenger. Inotropic and antihypertensive. Smooth muscle relaxant/vasodilator. Glucose transporter inhibitor. Platelet aggregation inhibitor....
| Keywords: | Boforsin, Colforsin, Coleonol, NSC 357088, NSC 375489 |
| Application: | Cell permeable adenylate cyclase activator |
| CAS | 66575-29-9 |
| MW: | 410,5 D |
From 22.00€
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AOH1996
Item number: AG-CR1-3553-M005
AOH1996 is an orally available and metabolically stable small molecule PCNA inhibitor, which selectively kills cancer cells, with a median concentration of about 300 nM for 50% growth inhibition. AOH1996 was not significantly toxic to non-malignant cells, even up to 10 µM. AOH1996 enhances the interaction between...
| Keywords: | NSC789796, N-(2-((2-(3-Methoxyphenoxy)phenyl)amino)-2-oxoethyl)-1-naphthamide |
| CAS | 2089314-64-5 |
| MW: | 426.5 D |
From 132.00€
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Staurosporine
Item number: AG-CN2-0022-M001
Isolated from Streptomyces spiralis. Antibiotic. Antifungal and anti-yeast activity. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-induced platelet aggregation. Potent, cell permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases. Inhibits protein...
| Keywords: | Antibiotic AM2282, Antibiotic 230, CCRIS 3272 |
| Application: | Protein kinase inhibitor, Apoptosis inducer |
| CAS | 62996-74-1 |
| MW: | 466,5 D |
From 50.00€
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COVID-19 Research
SARS-CoV-2 Inhibitor Screening Kit
Item number: AG-48B-0001-KI01
To screen compounds that inhibit the binding of the viral protein SARS-CoV-2 Spike Protein (RBD) to its human receptor ACE2. Coronaviruses (CoVs) are enveloped non-segmented positive-sense single-stranded RNA viruses and can infect respiratory, gastrointestinal, hepatic and central nervous system of human and many...
| Keywords: | COVID-19 Inhibitor Screening Kit, 2019-nCoV Inhibitor Screening Kit, 2019-nCoV Spike Protein S1 (RBD)/ACE2 Inhibitor... |
| Application: | Compound Screening |
| Species reactivity: | human |
737.00€
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Fc (LALA-PG)-KIH (human) IgG1 Control (rec.)
Item number: AG-35B-0018-C050
Negative control in experiments with recombinant proteins fused to human IgG1 Fc (LALA-PG)-KIH (Knobs-into-Holes) (e.g. Prod. No. AG-40B-0248). This protein is not an appropriate negative control for other standard Fc protein constructs. The protein Fc (LALA-PG)-KIH (human) IgG1 Control (rec.) is produced by using...
| Keywords: | Ig gamma-1 chain C region, Ig gamma-1 chain C region EU, Ig gamma-1 chain C region NIE, Ig gamma-1 chain C region KOL,... |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 28 kD |
341.00€
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IL-38 (human) (rec.) (His)
Item number: AG-40A-0191Y-3010
IL-38 (IL-1F10) mRNA is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-1F10 in the inflammatory response. It has been reported that removal of the N-terminus domain of the interleukins of the IL-1F...
| Keywords: | FIL1T, IL-38, FKSG75, IL-1HY2, IL-1F10, IL-1 theta, FIL1 theta, Interleukin-38, Interleukin-1 HY2, Interleukin-1 theta,... |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 18 kD |
From 264.00€
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Fc (LALA-PG)-KIH (human):GDF15 (mouse) (rec.)
Item number: AG-40B-0245-C050
Growth and differentiation factor 15 (GDF15, also known as macrophage inhibitory cytokine-1 (MIC-1)), is a member of the transforming growth factor (TGF)-beta superfamily and was initially identified in activated macrophages. GDF15 acts through a recently identified receptor called Glial-derived Neurotrophic Factor...
| Keywords: | MIC-1, GDF-15, Growth/differentiation factor 15, Macrophage inhibitory cytokine 1 |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 4530 kD |
440.00€
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Fc (LALA-PG)-KIH (human):Irisin (monomeric) (rec.)
Item number: AG-40B-0246-C050
Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the...
| Keywords: | FNDC5, FRCP2 |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 5530 kD |
440.00€
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IL-23 (mouse):Fc (LALA-PG)-KIH (human) (rec.)
Item number: AG-40B-0248-C050
Interleukin-12 (IL-12) family members are heterodimer glycoproteins, composed of two covalently linked subunits, alpha and beta chains. The alpha-subunit consists of IL-23p19, IL-27p28, and IL-12p35, and the beta-subunit includes IL-12p40 and Epstein-Barr virus-induced gene (Ebi3). IL-12 members bind to cognate...
| Keywords: | Il23a, IL-23-A, IL-23p19, IL-23 subunit alpha, Interleukin-23 subunit p19, Interleukin-23 subunit alpha |
| Expressed in: | Hamster cells |
| Origin: | mouse |
| MW: | 7555 kD |
440.00€
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IL-27 (mouse):Fc (LALA-PG)-KIH (human) (rec.)
Item number: AG-40B-0249-C050
Interleukin-12 (IL-12) family members are heterodimer glycoproteins, composed of two covalently linked subunits, alpha and beta chains. The alpha-subunit consists of IL-23p19, IL-27p28, and IL-12p35, and the beta-subunit includes IL-12p40 and Epstein-Barr virus-induced gene (Ebi3). IL-12 members bind to cognate...
| Keywords: | p28, Il27, Il27a, IL27-A, IL-27-A, IL-27 subunit alpha, Interleukin-27 subunit alpha |
| Expressed in: | Hamster cells |
| Origin: | mouse |
| MW: | 6260 kD |
440.00€
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