Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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UK 59811 hydrochloride
Item number: TGM-T36808-25mg
Description: Blocks CaVAb, a site-directed mutant of bacterial NaVAb with full voltage-dependent Ca2+ channel function (IC50 = 194 nM). Target: Others. References: Tang et al (2016) Structural basis for inhibition of a voltage-gated Ca2+ channel by Ca2+ antagonist drugs. Nature 537 117 PMID:27556947
From 95.00€
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uPSEM 792 hydrochloride
Item number: TGM-T36810-25mg
Description: Ultrapotent PSEM (uPSEM) agonist for PSAM4-GlyR and PSAM4-5HT3 (Ki = 0.7 nM for PSAM4-GlyR and 10,000-fold agonist selectivity for PSAM4-GlyR over alpha7-GlyR, alpha7-5HT3, and 5HT3-R, and 230-fold selectivity over alpha4beta2 nAChR. Also weak partial agonist (~10 %) at alpha4beta2 nAChR. Retains the...
From 279.00€
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Acetoacetyl Coenzyme A (sodium salt hydrate)
Item number: TGM-T36827-10mg
Description: Acetoacetyl-coenzyme A (acetoacetyl-CoA) is a precursor to HMG-CoA in the isoprenoid pathway.[1],[2] It is reversibly converted to acetyl-CoA by acetoacetyl-CoA thiolase in the mitochondria. Acetoacetyl-CoA thiolase (T2) deficiency results in a build-up of ketone bodies leading to intermittent...
| Keywords: | Acetoacetyl-CoA |
From 320.00€
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rCRAMP (rat) acetate
Item number: TGM-T40473L-100mg
Description: rCRAMP (rat) acetate, a cathelin-related antimicrobial peptide, exhibits antibacterial activity in rat brain peptide/protein extracts. Target: Antibacterial. References: Peter Bergman, et al. The antimicrobial peptide rCRAMP is present in the central nervous system of the rat. J Neurochem. 2005...
| Keywords: | rCRAMP (rat) acetate (376364-38-4 Free base) |
From 77.00€
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THP-PEG10-OH
Item number: TGM-T40531-100mg
Description: THP-PEG10-OH is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells. Target: Others. References: An S, et al. Small-molecule PROTACs: An emerging...
| Keywords: | THP-PEG10-OH |
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NH2-PEG2-C6-Cl hydrochloride
Item number: TGM-T40858L-100mg
Description: NH2-PEG2-C6-Cl hydrochloride is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules. Target: PROTACs. Smiles: Cl.NCCOCCOCCC CCCCl
| Keywords: | NH2-PEG2-C6-Cl hydrochloride(744203-60-9 Free base) |
| MW: | 260.2 D |
From 34.00€
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ADTL-SA1215
Item number: TGM-T40891-2mg
Description: ADTL-SA1215 is a selective SIRT3 activator with SIRT3 deacetylase activity that inhibits the proliferation and migration of human breast cancer MDA-MB-231 cells through the SIRT3-driven autophagy/mitochondrial autophagy signaling pathway, and can be used in the study of triple negative breast cancer....
| Keywords: | ADTLSA1215, ADTL SA1215 |
| MW: | 657.32 D |
282.00€
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Fmoc-Lys(Boc)-Ser(psi(Me,Me)pro)-OH
Item number: TGM-T41118-500mg
Description: Fmoc-Lys(Boc)-Ser(psi(Me,Me)pro)-OH is a dipeptide composed of an Fmoc-protected lysine with a Boc group and a serine residue containing a pseudo-proline [psi(Me,Me)pro] modification. Smiles: C(OC(N[C@H](C(=O)N1[C@H](C(O)=O)COC1(C)C)CCCCNC(OC(C)(C)C)=O)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3
| MW: | 595.68 D |
31.00€
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ND1-YL2
Item number: TGM-T41146-5mg
Description: ND1-YL2 is a peptide-based PROTAC(R)Degrader of steroid receptor co-activator 1 (SRC-1, also known as nuclear receptor coactivator 1, NCOA1). ND1-YL2 is composed of a stapled peptide that binds SRC-1 (YL2) joined by a linker to a tetrapeptide that binds UBR box domains. Upon ternary complex formation,...
| Keywords: | ND1-YL2 |
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BOP-JF549
Item number: TGM-T41149-100ug
Description: BOP-JF549 is a fluorescent dual alpha9beta1/alpha4beta1 integrin inhibitor. Comprises BOP conjugated to Janelia Fluor(R) 549. Fluorogenic: fluoresces only once bound to integrins, enabling hassle-free no-wash experiments. Bright and photostable, enabling live cell tracking of integrin receptors over...
| Keywords: | BOP-JF549 |
1,630.00€
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R-BC154
Item number: TGM-T41152-5mg
Description: R-BC154 is a high affinity fluorescent alpha4beta1/alpha9beta1 inhibitor (Kdvalues are 12.7 and 38 nM, respectively), fluorescent version of BOP. Rapidly and preferentially mobilizes HSCs and progenitorsin vivo. Excitation maximum, 561 nm, emissiosn maximum, 585 nm. Target: Others. References: Cao et al...
| Keywords: | R-BC154 |
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BOP-JF646
Item number: TGM-T41153-100ug
Description: BOP-JF646 is a fluorescent dual alpha9beta1/alpha4beta1 integrin inhibitor. Comprises BOP conjugated to Janelia Fluor(R)646. Fluorogenic: fluoresces only once bound to integrins, enabling hassle-free no-wash experiments. Bright and photostable, enabling live cell tracking of integrin receptors over long...
| Keywords: | BOP-JF646 |
1,630.00€
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