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Products from South Bay Bio
South Bay Bio is a biotechnology company dedicated to providing high-troughput screening (HTS)-related products with a focus on the ubiquitin proteasome system. The company was formed in the San Francisco Bay area to support local biotechnology companies. The headquarters is located in San José, California.
More information at: www.adipogen.com/southbaybio
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Item number: SBB-PS0124-C050
Protein. Human ubiquitin (aa1-76) (Accession Nr. P0CG47) with a C-terminal propargylamide group and a N-terminal HA-tag. Source: E. coli. Liquid. In 50mM MES pH 6.0, 100mM sodium chloride. Purity: >97% (LCMS). Ubiquitin is a small (8.5kDa) regulatory protein that has been found in almost all tissues of eukaryotic...
Keywords: | HA-Ub-PA, HA-Ubiquitin-PA, HA-Ubiquitin-Propargylamide |
Expressed in: | E. coli |
Origin: | human |
MW: | 10 kD |
420.00€
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Item number: SBB-PS0001-C050
Ubiquitin is a 76 amino acid post-translational modifier expressed throughout all tissues in eukaryotic organisms. The many roles of ubiquitin modification include proteasomal degradation, signal transduction, inflammatory response and DNA damage repair. Ubiquitin modification occurs through a pyramidal cascade of...
Keywords: | UBB, Ubiquitin B |
Application: | Assays |
Expressed in: | E.coli |
Origin: | human |
MW: | 9 kD |
405.00€
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Item number: SBB-PS0003-C050
NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8) is a ubiquitin like protein that plays an important role in regulating development and the cell cycle. NEDD8 is conjugated to a target protein via a signaling cascade similar to ubiquitin: a NEDD8 specific E1 activating enzyme (APPBP1/UBA3)...
Keywords: | Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 8, Neddylin, Rub1 |
Application: | Assays |
Expressed in: | E.coli |
Origin: | human |
MW: | 9 kD |
497.00€
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Item number: SBB-PS0006-M002
Lyophilized powder. Soluble in DMSO. Z-LLE-AMC is a fluorogenic peptide substrate for measuring caspase-like activity of the proteasome. Hydrolysis of this substrate by the beta1-subunit of the 20S proteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at 445nm. This...
Keywords: | Proteasome Substrate II |
Application: | Fluorogenic peptide substrate |
MW: | 664,8 D |
234.00€
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Item number: SBB-PS0007-M002
Lyophilized powder. Soluble in DMSO. Ac-PAL-AMC is a fluorogenic peptide substrate for measuring caspase-like activity of the immunoproteasome. Hydrolysis of this substrate by the beta1i-subunit of the immunoproteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at 445nm....
Keywords: | Proteasome Substrate |
Application: | Fluorogenic peptide substrate |
MW: | 498,6 D |
234.00€
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Item number: SBB-PS0010-M002
Lyophilized powder. Soluble in DMSO. Suc-LLVY-AMC is a fluorogenic substrate for measuring the chymotrypsin-like peptidase activity of the 20S and 26S proteasome, calpains and other chymotrypsin-like proteases. Cleavage of the peptide by the enzymes liberates the fluorophore AMC which generates strong increase in...
Keywords: | Proteasome Substrate |
Application: | Fluorogenic peptide substrate |
MW: | 763,9 D |
117.00€
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Item number: SBB-KP0038-KI01
South Bay Bio's kit is designed to test for specific activity of 20S proteasome. The kit provides purified 20S proteasome and is designed to test for Chymotrypsin-like activity (Suc-LLVY-AMC), Caspase-like activity of the proteasome subunits beta1/PSMB6 (LLE-AMC) and Chymotrypsin-like activity of beta5/PSMB5...
Application: | Compound Screening |
717.00€
*
Item number: SBB-CE0019-C100
UBE2D3 [UbcH5c] is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2D3 via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2D3-Ub thioester. UBE2D3 is capable of...
Keywords: | Ubiquitin-conjugating Enzyme H5c, PUBC, UBC5C, Ubiquitin-protein Ligase D3, p53-regulated Ubiquitin-conjugating Enzyme |
Application: | Assays |
Expressed in: | E.coli |
Origin: | human |
MW: | 17 kD |
396.00€
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Item number: SBB-CE0020-C100
UBE2L3 (UbcH7) is an E2 ubiquitin conjugating enzyme and accepts ubiquitin from an E1 activating enzyme via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2L3-Ub thioester. UBE2L3 transfers active ubiquitin molecules...
Keywords: | Ubiquitin-conjugating Enzyme E2 L3, E2-F1, L-UBC, UBCE7, UbcM4, UBE2L3, Ubiquitin-protein Ligase L3 |
Application: | Assays |
Expressed in: | E.coli |
Origin: | human |
MW: | 18 kD |
396.00€
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Item number: SBB-PP0004-C025
The 20S immunoproteasome is structurally similar to constitutive 26S proteasome. The 20S core of immunoproteasome contains two outer rings composed of alpha-subunits, and two internal 7-subunit containing rings each possessing 3 specific subunits responsible for proteasome catalytic activity. In immunoproteasomes...
Application: | Assays |
Expressed in: | Human cells |
Origin: | human |
MW: | 700 kD |
582.00€
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Item number: SBB-PS0002-C050
ISG15 (Interferon Stimulated Gene, 15kDa) is a ubiquitin-like modifier which initiates innate immune response by activating RIG-I signaling, stimulating NK-cell proliferation, inhibiting viral budding and acting as an IFNgamma-inducing cytokine. ISG15 contains two tandem ubiquitin homology domains and is...
Keywords: | ISG15 Ubiquitin-like Modifier, G1P2, IFI15, IP17, UCRP |
Application: | Assays |
Expressed in: | E.coli |
Origin: | human |
MW: | 18 kD |
497.00€
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Item number: SBB-PS0008-M002
Lyophilized powder. Soluble in DMSO. Ac-WLA-AMC is a fluorogenic peptid substrate for measuring chymotrypsin-like activity of the proteasome. Hydrolysis of this substrate by the beta5-subunit of the 20S proteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at 445nm. This...
Keywords: | Proteasome Substrate |
Application: | Fluorogenic peptide substrate |
MW: | 587,7 D |
234.00€
*