87 products were found matching "K05853"!
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Thapsigargin
Item number: Cay10522-1
Thapsigargin is an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA, IC50 = ~30 nM for the rat liver microsomal enzyme), an ER stress inducer, and a sesquiterpene lactone that has been found in Thapsia. It increases intracellular calcium levels in isolated rat hepatocytes (EC50 = ~80 nM) and...
| Keywords: | (3S,3aS,4R,6R,7S,8R)-6-acetoxy-4-(butyryloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-(((Z)-2-methylbut-2-enoyl)oxy)-2-oxo-2,3,3a... |
| Application: | SERCA inhibitor |
| CAS | 67526-95-8 |
| MW: | 650.8 D |
From 75.00€
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Thapsigargin (high purity)
Item number: AG-CN2-0003-M001
Colorless to white amorphous powder. Soluble in DMSO or 100% ethanol. Chemical. CAS: 67526-95-8. Formula: C34H50O12. MW: 650.8. Isolated from Thapsia garganica. Intracellular Ca2+ signaling probe. Specific and sensitive inhibitor of SERCA. Non-TPA/PMA tumor promoter. Histamine release inducer. Apoptosis inducer....
| Application: | SERCA inhibitor, Ca2+ releaser |
| CAS | 67526-95-8 |
| MW: | 650,8 D |
From 77.00€
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Anti-ATP2A1
Item number: ATA-HPA066701.100
Polyclonal Antibody against Human ATP2A1, Gene description: ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, Alternative Gene Names: ATP2A, SERCA1, Validated applications: IHC, Uniprot ID: O14983, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein...
| Keywords: | Anti-ATP2A1, Anti-SERCA1, Anti-Calcium pump 1, Anti-SR Ca(2+)-ATPase 1, Anti-Endoplasmic reticulum class 1/2 Ca(2+)... |
| Application: | IHC |
| Host: | Rabbit |
| Species reactivity: | human |
477.00€
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CDN1163
Item number: TGM-T7373-100mg
Description: CDN1163 is a small molecule activator of sarco/endoplasmic reticulum Ca2+-ATPase (SERCA). Target: Calcium Channel. Smiles: CC(C)Oc1ccc(cc1)C(=O)Nc1cccc2ccc(C)nc12. References: Kang S , Dahl R , Hsieh W , et al. Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA)...
| Application: | Allosteric SERCA2 activator |
| CAS | 892711-75-0 |
| MW: | 320.39 D |
From 40.00€
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Mipsagargin
Item number: TGM-T8683-10mg
Description: Mipsagargin (G-202) is a novel antibiotic that inhibits DNA biosynthesis. Target: Others, Drug-Linker Conjugates for ADC. Smiles: CC1=C2[C@]([C@H](OC(CCCCCCC)=O)[C@H]1OC(/C(=C\C)/C)=O)([C@](OC(C)=O)(C)C[C@H](OC(CCCCCCCCCC...
| Keywords: | G-202 |
| Application: | Targets P-type Ca2+ transporter type 2A [EC:7.2.2.10] (ATP2A) |
| CAS | 1245732-48-2 |
| MW: | 1409.52 D |
From 133.00€
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Thapsigargin
Item number: TGM-TQ0302-1mg
Description: Thapsigargin is a natural product, an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) and an endoplasmic reticulum stress inducer. Thapsigargin increases cytoplasmic calcium concentration by blocking the ability of cells to pump calcium into the sarcoplasmic and endoplasmic...
| Application: | SERCA inhibitor, Ca2+ releaser |
| CAS | 67526-95-8 |
| MW: | 650.75 D |
From 81.00€
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Cyclopiazonic acid
Item number: TGM-T15027-10mg
Description: Cyclopiazonic acid (CPA) is a neurotoxic secondary metabolite (SM) made by A. flavus. Cyclopiazonic acid (CPA) is an endoplasmic reticulum calcium ATPase (Ca2+ATPase, SERCA)nanomolar inhibitor and a potent inducer of cell death in plants. Target: Calcium Channel. Smiles:...
| Application: | SERCA inhibitor, mycotoxin |
| CAS | 18172-33-3 |
| MW: | 336.38 D |
From 83.00€
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N106
Item number: TGM-T28124-100mg
Description: N106 is an activator of the SUMO-activating enzyme, E1 ligase, and triggers intrinsic sumoylation of SERCA2a. N106 can be used in studies about heart failure. Target: E1/E2/E3 Enzyme. Smiles: COc1ccc(cc1)-c1nnc(Nc2nc3c(OC)cccc3s2)o1. References: Kho C, et al. Small-molecule activation of SERCA2a...
| Keywords: | N 106, N-106 |
| Application: | SERCA2A sumoylation activator |
| CAS | 862974-25-2 |
| MW: | 354.38 D |
From 43.00€
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Cyclopiazonic Acid
Item number: Cay11326-1
Cyclopiazonic acid is a mycotoxin that has been found in Penicillium and Aspergillus and an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA, IC50 = 0.6 µM). In vivo, cyclopiazonic acid (11-14 mg/kg) induces ptosis, hypothermia, tremor, and cachexia, as well as induces lethality (LD50 = 13 mg/kg),...
| Keywords: | CPA, NSC 117181,... |
| Application: | SERCA inhibitor, mycotoxin |
| CAS | 18172-33-3 |
| MW: | 336.4 D |
From 35.00€
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Anti-ATP2A1
Item number: CSB-PA004072.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-ATP2A1, Anti-SERCA1, Anti-Calcium pump 1, Anti-SR Ca(2+)-ATPase 1, Anti-Endoplasmic reticulum class 1/2 Ca(2+)... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 126.00€
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Anti-ATP2A2
Item number: CSB-PA005808.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-ATP2B, Anti-SERCA2, Anti-ATP2A2, EC=7.2.2.10, Anti-Calcium pump 2, Anti-SR Ca(2+)-ATPase 2, Anti-Endoplasmic... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
126.00€
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Anti-ATP2A3
Item number: CSB-PA088870.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ATP2A3. Antigen Species: Human
| Keywords: | Anti-ATP2A3, Anti-SERCA3, EC=7.2.2.10, Anti-Calcium pump 3, Anti-SR Ca(2+)-ATPase 3, Anti-Sarcoplasmic/endoplasmic... |
| Application: | ELISA, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
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