22 products were found matching "K04272"!

UDP is the diphosphate of the nucleoside uridine. It is a specific agonist of the P2Y purinoceptor P2Y6 (EC50 = 13 nM for human P2Y6), stimulating the production of inflammatory mediators, phagocytosis, and vasoconstriction. UDP also acts as an antagonist of P2Y14, whose agonists include UDP-glucose (Cay-15602),...

MRS2578 is an antagonist of the purinergic P2Y6 receptor (IC50s = 37 and 98 nM for human and rat receptors, respectively). It is without effect at other purinergic receptors. MRS2578 is used to study the cellular and physiological roles of P2Y6.Formal Name:...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. P2Y purinoceptor 6 is a protein that in humans is encoded by the P2RY6 gene. The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein...

UDP-beta-S is an agonist of the purinergic P2Y6 receptor. It selectively induces inositol phosphate accumulation in 1321N1 cells expressing P2Y6 receptors (EC50 = 28 nM) over those expressing P2Y1, P2Y2, or P2Y4 receptors at 10 µM. UDP-beta-S (1 µM) induces DNA synthesis in isolated rat aorta smooth muscle...

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: P2RY6. Antigen Species: Human

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: P2RY6. Antigen Species: Human

Description: MRS2578, an effective P2Y6 receptor antagonist with IC50 of 37 nM, shows insignificant inhibition at P2Y1, P2Y2, P2Y4, and P2Y11 receptors. Target: Apoptosis, P2Y Receptor. Smiles: S=C=Nc1cccc(NC(=S)NCCCCNC(=S)Nc2cccc(c2)N=C=S)c1. References: Mamedova LK, et al. Biochem Pharmacol, 2004, 67(9), 1763-1770.

P2Y6 Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system [The Uniprot Consortium]

Protein function: Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. [The UniProt Consortium]

Protein function: Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. [The UniProt Consortium]

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....