MRS2578

MRS2578 is an antagonist of the purinergic P2Y6 receptor (IC50s = 37 and 98 nM for human and rat receptors, respectively). It is without effect at other purinergic receptors. MRS2578 is used to study the cellular and physiological roles of P2Y6.Formal Name: N,N''-1,4-butanediylbis[N'-(3-isothiocyanatophenyl)-thiourea. CAS Number: 711019-86-2. Molecular Formula: C20H20N6S4. Formula Weight: 472.7. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/ml, DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml, DMSO: 10 mg/ml. lambdamax: 217, 273 nm. SMILES: S=C(NCCCCNC(NC1=CC=CC(N=C=S)=C1)=S)NC2=CC(N=C=S)=CC=C2. InChi Code: InChI=1S/C20H20N6S4/c27-13-23-15-5-3-7-17(11-15)25-19(29)21-9-1-2-10-22-20(30)26-18-8-4-6-16(12-18)24-14-28/h3-8,11-12H,1-2,9-10H2,(H2,21,25,29)(H2,22,26,30). InChi Key: QOHNRGHTJPFMSL-UHFFFAOYSA-N.