Oleandrin is a glycoside that has been found in N. oleander and has diverse biological activities. It inhibits NF-kappaB activation induced by hydrogen peroxide, LPS, okadaic acid (Cay-10011490), ceramide, or TNF in U937 cells when used at a concentration of 1 µg/ml. Oleandrin inhibits transmissible gastroenteritis...

Description: 1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin are known to inhibit the Na, K-ATPase pump, resulting in a consequent increase in calcium influx in heart muscle....