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PP242
PP242

Item number: Cay13643-1

The mammalian target of rapamycin (mTOR) is a serine-threonine kinase that is central to two protein complexes, mTORC1 and mTORC2. These complexes are differentially regulated (e.g., only mTORC1 is sensitive to rapamycin) and regulate different pathways. PP242 is an inhibitor of the active site of mTOR kinase in...
Keywords: 2-[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-1H-indol-5-ol
Application: mTOR kinase inhibitor
CAS 1092351-67-1
MW: 308.3 D
From 43.00€ *
Review
PP-242
PP-242

Item number: LKT-P6004.1

mTOR inhibitor.
Keywords: Pp242, Torkinib
Application: mTOR inhibitor
CAS 1092351-67-1
MW: 308.34 D
From 115.00€ *
Review
PP-242
PP-242

Item number: SYN-1181-M001

Soluble in DMSO or ethanol. PP242 exhibits potent selectivity for mTOR over other PI3K family kinases such as p110 alpha - delta and DNA-PK, with IC(50) of 1.96µM, 2.2µM, 1.27µM, 0.102µM, and 0.408µM, respectively.
Keywords: PP242
Application: mTOR inhibitor
CAS 1092351-67-1
MW: 308,3 D
From 66.00€ *
Review