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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
375888.20 | 20 µg | - | - |
3 - 19 business days* |
606.00€
|
||
375888.100 | 100 µg | - | - |
3 - 19 business days* |
855.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Mediates pre-mRNA alternative splicing regulation. Component of the CRD-mediated complex that... more
Product information "Ybx1, Recombinant, Mouse, aa2-322, His-Tag (Nuclease-sensitive Element-binding Protein 1)"
Mediates pre-mRNA alternative splicing regulation. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes Cytoplasmic domain mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. Regulates the transcription of numerous genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds preferentially to 5'-[CU]CUGCG-3' motif in vitro. The secreted form acts as an Extracellular domain mitogen and stimulates cell migration and proliferation. Source: Recombinant protein corresponding to aa2-322 from mouse Ybx1, fused to His-Tag at N-terminal, expressed in Yeast. Molecular Weight: ~37.6kD, AA Sequence: SSEAETQQPPAAPAAALSAADTKPGSTGSGAGSGGPGGLTSAAPAGGDKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSKYAADRNHYRRYPRRRGPPRNYQQNYQNSESGEKNEGSESAPEGQAQQRRPYRRRRFPPYYMRRPYARRPQYSNPPVQGEVMEGADNQGAGEQGRPVRQNMYRGYRPRFRRGPPRQRQPREDGNEEDKENQGDETQGQQPPQRRYRRNFNYRRRRPENPKPQDGKETKAADPPAENSSAPEAEQGGAE, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | DBPB, YB-1, Ybx1, CBF-A, Msy-1, EFI-A, DNA-binding protein B, Y-box-binding protein 1, Y-box transcription factor, Enhancer factor I subunit A, Nuclease-sensitive element-binding protein 1, CCAAT-binding transcription factor I subunit A |
Supplier: | United States Biological |
Supplier-Nr: | 375888 |
Properties
Conjugate: | No |
MW: | 37,6 |
Format: | Highly Purified |
Database Information
KEGG ID : | K09276 | Matching products |
UniProt ID : | P62960 | Matching products |
Gene ID | GeneID 22608 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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