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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay10320-500 | 500 µg | - |
6 - 10 business days* |
805.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Methylation of lysine can promote transcriptional activation or repression and is critical in... more
Product information "SET7/9 (human recombinant)"
Methylation of lysine can promote transcriptional activation or repression and is critical in regulating histone function. Lysine residues can be mono-, di-, or tri-methylated, and unlike most SET proteins, SET7/9 is exclusively a mono-methylase. SET7/9 methylates histone H3, tumor suppressor p53, and transcription factor TAF10. Recently, SET7/9 was shown to catalyze methylation of p53 in response to DNA damage thereby activating p53 for subsequent acetylation. SET7/9 is able to modulate p53 activity in a human cancer cell line, implying that it may play a significant role in human tumorigenesis.Synonyms: KMT7, SETD7, SETD7/9, SET Domain-containing Protein 7/9. Purity: >95% estimated by SDS-PAGE. Source: Active recombinant N-terminal His-tagged SET7/9 purified from E. coli. Amino Acids: 1-366 (full-length). MW: 43.3 kDa. Formulation: (Request formulation change), 50 mM HEPES, pH 7.2, 100 mM sodium chloride, and 20% glycerol. UniProt Accession #: Q8WTS6.
Keywords: | SETD7, SET7/9, SET7/9, KIAA1717, H3-K4-HMTase SETD7, H3-K4-HMTase SETD7, Lysine N-methyltransferase 7, Lysine N-methyltransferase 7, SET domain-containing protein 7, SET domain-containing protein 7, Histone H3-K4 methyltransferase SETD7, Histone H3-K4 met |
Supplier: | Cayman Chemical |
Supplier-Nr: | 10320 |
Properties
Application: | Enzyme activity |
Conjugate: | No |
Host: | E.coli |
MW: | 43.3 kD |
Purity: | >95% estimated by SDS-PAGE |
Database Information
KEGG ID : | K11431 | Matching products |
UniProt ID : | Q8WTS6 | Matching products |
Gene ID | GeneID 80854 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -80°C (International: -80°C) |
Signal Word: | Warning |
GHS Hazard Pictograms: |
|
H Phrases: | H316, H319 |
P Phrases: | P264, P280, P305+351+338, P332+313, P337+313 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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