PD-1/PDCD1 mFc Chimera, Human

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
GSC-Z05735-100	100 µg		-		7 - 10 business days*		457.00€
GSC-Z05735-500	500 µg		-		7 - 10 business days*		1,505.00€

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Programmed Death-1 receptor (PD-1), also known as CD279, is type I transmembrane protein... more

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Product information "PD-1/PDCD1 mFc Chimera, Human"

Programmed Death-1 receptor (PD-1), also known as CD279, is type I transmembrane protein belonging to the CD28 family of immune regulatory receptors.PD1 is a inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self. Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:21276005). Following T-cell receptor (TCR) engagement, PDCD1 associates with CD3-TCR in the immunological synapse and directly inhibits T-cell activation.

Keywords:	PDCD1, Programmed cell death protein 1
Supplier:	GenScript
Supplier-Nr:	Z05735

Properties

Conjugate:	No
Species reactivity:	human
MW:	41.6 kD
Purity:	>95% (Bis-Tris PAGE)

Database Information

KEGG ID :	K06744 \| Matching products
UniProt ID :	Q15116 \| Matching products
Gene ID :	GeneID 5133 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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