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BMS 1166 (hydrochloride)
BMS 1166 (hydrochloride)

Item number: Cay27774-1

BMS 1166 is an inhibitor of the protein-protein interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 that has an IC50 value of 1.4 nM in a homologous time-resolved fluorescence (HTRF) assay. It increases the activation of Jurkat cells expressing PD-1 in co-culture with CHO cells expressing PD-L1...
Keywords: (4R)-1-[[5-chloro-2-[(3-cyanophenyl)methoxy]-4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]methoxy]phenyl]methyl...
Application: PD-1/PD-L1 interaction inhibitor
CAS 2113650-05-6
MW: 677.6 D
From 62.00€ *
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PD-1 (Human) sgRNA-MS2 Lentivirus (Integrating)
PD-1 (Human) sgRNA-MS2 Lentivirus (Integrating)

Item number: BPS-78190

The binding of Programmed Cell Death Protein 1 (PD-1), a receptor expressed on activated T-cells, to its ligands PD-L1 and PD-L2, negatively regulates immune responses. PD-1 ligands are found on most cancers, and the PD-1:PD-L1/2 interaction inhibits T-cell activity and enables cancer cells to escape immune...
Keywords: hPD-1, CD279, Protein PD-1, Programmed cell death protein 1,
Application: CRISPR studies
Reactivity: Human
998.00€ *
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NP19
NP19

Item number: Cay31791-10

NP19 is an inhibitor of the protein-protein interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 (IC50 = 12.5 nM in a homogenous time-resolved fluorescence (HTRF) assay). It increases IFN-gamma production by isolated human peripheral blood mononuclear cells (PBMCs) in co-culture with anti-CD3...
Keywords: N-[[5-chloro-2-[(3-cyanophenyl)methoxy]-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl]methyl]-2-methyl-alanine
Application: PD-1/PD-L1 interaction inhibitor
CAS 2377916-66-8
MW: 555.1 D
From 99.00€ *
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CAY10774
CAY10774

Item number: Cay32569-10

CAY10774 is an inhibitor of the protein-protein interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 (IC50 = 15 nM in a homologous time-resolved fret (HTRF) assay). It increases the activation of Jurkat cells expressing PD-1 in co-culture with artificial antigen-presenting cells (aAPCs) expressing...
Keywords: (S)-1-(3-bromo-4-((2-bromo-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylic acid
Application: PD-1/PD-L1 interaction inhibitor
MW: 559.3 D
From 32.00€ *
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Anti-PD-1/CD279 (N-Term) Rabbit
Anti-PD-1/CD279 (N-Term) Rabbit

Item number: Cay32253-100

Programmed cell death protein 1 (PD-1), also known as CD279, is a cell surface receptor belonging to the immunoglobulin superfamily that is involved in regulation and attenuation of the adaptive immune response. It is a 288-amino acid type I transmembrane protein encoded by the PDCD1 gene in humans and is comprised...
Keywords: CD279, PDCD1, Programmed Cell Death Protein 1
Application: IHC, WB
407.00€ *
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PD-1 sgRNA-MS2 for CRISPRa (Plasmid)
PD-1 sgRNA-MS2 for CRISPRa (Plasmid)

Item number: BPS-78091

The binding of Programmed Cell Death Protein 1 (PD-1), a receptor expressed on activated T-cells, to its ligands, PD-L1 and PD-L2, negatively regulates immune responses. PD-1 ligands are found on most cancers, and the PD-1:PD-L1/2 interaction inhibits T-cell activity and enables cancer cells to escape immune...
Keywords: hPD-1, CD279, Protein PD-1, Programmed cell death protein 1
Application: Endogenous PD-1 expression activation in CRISPRa (SAM) cells
Reactivity: Human
121.00€ *
Review
PDCD1/PD-1/CD279 (C-6His-Avi) Biotinylated (recombinant human)
PDCD1/PD-1/CD279 (C-6His-Avi) Biotinylated (recombinant...

Item number: E-PKSH033853.100

Protein Construction: Biotinylated Recombinant Human Programmed Cell Death Protein 1 is produced by our Mammalian expression system and the target gene encoding Pro21-Gln167 is expressed with a 6His, Avi tag at the C-terminus. Sequence: Pro21-Gln167. Fusion tag: C-6His-Avi Endotoxin: < 1.0 EU per µg as determined by...
Keywords: CD279, hPD-1, Protein PD-1, Programmed cell death protein 1, Recombinant Human PDCD1/PD-1/CD279 (C-6His-Avi) Biotinylated
Reactivity: Human
MW: 19.2 kD
From 373.00€ *
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Anti-PDCD1 / PD1 / CD279 (Programmed Cell Death 1) Monoclonal Antibody (Clone: PDCD1/2720)
Anti-PDCD1 / PD1 / CD279 (Programmed Cell Death 1)...

Item number: ABE-36-2904-100

PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and sµggests a unique cell of origin for this...
Keywords: Anti-CD279, Anti-hPD-1, Anti-Protein PD-1, Anti-Programmed cell death protein 1, Anti-PDCD1 / PD1 / CD279 (Programmed Cell...
Application: ELISA, IHC
Reactivity: Human
From 287.00€ *
Review
Anti-PDCD1 / PD1 / CD279 (Programmed Cell Death 1) Monoclonal Antibody (Clone: NAT105)
Anti-PDCD1 / PD1 / CD279 (Programmed Cell Death 1)...

Item number: ABE-36-2905-100

PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and sµggests a unique cell of origin for this...
Keywords: Anti-CD279, Anti-hPD-1, Anti-Protein PD-1, Anti-Programmed cell death protein 1, Anti-PDCD1 / PD1 / CD279 (Programmed Cell...
Application: FC, IF, IHC
Reactivity: Human
From 287.00€ *
Review
Anti-PDCD1 / PD1 / CD279 (Programmed Cell Death 1) Monoclonal Antibody (Clone: PDCD1/1410R)
Anti-PDCD1 / PD1 / CD279 (Programmed Cell Death 1)...

Item number: ABE-36-2906-100

PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and sµggests a unique cell of origin for this...
Keywords: Anti-CD279, Anti-hPD-1, Anti-Protein PD-1, Anti-Programmed cell death protein 1, Anti-PDCD1 / PD1 / CD279 (Programmed Cell...
Application: IHC
Reactivity: Human
From 287.00€ *
Review
Anti-PDCD1 / PD1 / CD279 (Programmed Cell Death 1) Polyclonal Antibody
Anti-PDCD1 / PD1 / CD279 (Programmed Cell Death 1)...

Item number: ABE-36-2907-100

PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and sµggests a unique cell of origin for this...
Keywords: Anti-CD279, Anti-hPD-1, Anti-Protein PD-1, Anti-Programmed cell death protein 1, Anti-PDCD1 / PD1 / CD279 (Programmed Cell...
Application: IHC
Reactivity: Human
From 287.00€ *
Review
Anti-PD1, Mouse Monoclonal Antibody (Clone: RMP1-14)
Anti-PD1, Mouse Monoclonal Antibody (Clone: RMP1-14)

Item number: ABE-36-3818-100

PD-1 is expressed on a subset of CD4-CD8-thymocytes, and on activated T and B cells. PD-1 is thoµght to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. PD-1 is transiently expressed...
Keywords: Anti-mPD-1, Anti-CD279, Anti-Protein PD-1, Anti-Programmed cell death protein 1, Anti-PD1, Mouse Monoclonal Antibody...
Application: ELISA, FC, IF
Reactivity: Mouse
From 287.00€ *
Review
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