909 products were found matching "K06744"!

Description: PD-1 Protein, Human, Recombinant (CHO, hFc) is expressed in CHO Cells. The accession number is Q15116.

Programmed cell death protein 1 (PD-1), also known as CD279, is a cell surface receptor belonging to the immunoglobulin superfamily that is involved in regulation and attenuation of the adaptive immune response. It is a 288-amino acid type I transmembrane protein encoded by the PDCD1 gene in humans and is composed...

Nivolumab, also known as BMS-936558, is a programmed death receptor-1 (PD-1) blocking human IgG4 antibody. This antibody is used in the treatment of several cancer types, from melanoma to Hodgkin lymphoma. PD-1 (Programmed Death Protein 1, CD279) is a transmembrane protein expressed on the surface of immune cells...

Pembrolizumab, also known as MK-3475, is a humanized IgG4 antibody able to inhibit the PD-1 (programmed cell death 1). PD-1 (Programmed Death Protein 1, CD279) is a transmembrane protein expressed on the surface of immune cells that binds to PD-L1 or PD-L2, inducing apoptosis of T cells and inhibiting immune...

The programmed cell death 1 protein (PD1) is an inhibitory receptor expressed on antigen activated T-cells that plays a critical role in the induction and maintenance of immune tolerance to self-antigens. Upon binding to its ligands CD274/PDCD1L1 (PD-L1) and CD273/PDCD1LG2 (PD-L2), PD1 is phosphorylated within its...

Protein function: Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen- specific manner. Possible cell death inducer, in association with other factors. [The UniProt Consortium]

Neutralizing human recombinant monoclonal antibody (clone 1B8, IgG1 subclass) recognizing the PD-L1 binding region of human PD-1, expressed in a 293 freestyle cell expression system. MW = 50 kDa and 25 kDa for the heavy and light chain portions, respectively.

The Naveni(R) PD1/PD-L1 BOND RX HRP is an in situ proximity ligation assay kit for the detection of the interaction of PD1 and PD-L1 using BOND RX/RXm Fully Automated Research Stainer. The kit has been validated on FFPE human tissue samples. Not recommend for mouse tissue. For research use only. Not for use in...

NaveniFlex MR Control kit is used together with NaveniFlex Cell/Tissue and Naveni Bright MR products as a control for the proximity ligation reagents, and to help the user identify positive signals.

Programmed cell death protein 1, also called PD-1 or PDCD1 is a protein that in humans is encoded by the PDCD1 gene. This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. By fluorescence in situ hybridization, the PDCD1 gene is mapped to 2q37.3. This protein is expressed in pro-B-cells...

Anti-PD-1 IgG antibody is a purified recombinant antibody which recognizes human PD1 antigen. This antibody has been functionally tested in two co-culture assays.

CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral...