744 products were found matching "Q15116"!

Product Description: Programmed Cell Death 1 (PDCD1), also known as PD-1 or CD279, is a cell surface receptor that plays a critical role in regulating the immune system's response to the body's own cells. It is encoded by the PDCD1 gene and belongs to the immunoglobulin superfamily. PD-1 is primarily expressed on...

Rosnilimab, also known as ANB030, is an monoclonal agonist antibody targeting PD-1 ( Programmed cell death protein 1). The binding of Programmed Cell Death Protein 1 (PD-1), also known as CD279, a receptor expressed on activated T cells, to its ligands PD-L1 and PD-L2, negatively regulates immune responses....

Toripalimab, also known as JS-001, is an humanized monoclonal antibody targeting PD-1 ( Programmed cell death protein 1). It blocks the interaction of PD-1 with its ligands. The binding of Programmed Cell Death Protein 1 (PD-1), also known as CD279, a receptor expressed on activated T cells, to its ligands PD-L1 and...

Sintilimab, also known as IBI308, is an humanized IgG4 monoclonal antibody targeting PD-1 ( Programmed cell death protein 1). It blocks the interaction of PD-1 with its ligands. The binding of Programmed Cell Death Protein 1 (PD-1), also known as CD279, a receptor expressed on activated T cells, to its ligands PD-L1...

The Naveni PD1/PD-L1 is an in situ proximity ligation assay kit for chromogenic (HRP) detection of the interaction of PD1 and PD-L1. This is the first commercial assay for detecting the interaction in situ, the kit gives a high signal-to-noise ratio and has an out-standing specificity. The kit has been validated on...

Description: PD-1 Protein, Human, Recombinant (CHO, hFc) is expressed in CHO Cells. The accession number is Q15116.

Programmed cell death protein 1 (PD-1), also known as CD279, is a cell surface receptor belonging to the immunoglobulin superfamily that is involved in regulation and attenuation of the adaptive immune response. It is a 288-amino acid type I transmembrane protein encoded by the PDCD1 gene in humans and is composed...

Nivolumab, also known as BMS-936558, is a programmed death receptor-1 (PD-1) blocking human IgG4 antibody. This antibody is used in the treatment of several cancer types, from melanoma to Hodgkin lymphoma. PD-1 (Programmed Death Protein 1, CD279) is a transmembrane protein expressed on the surface of immune cells...

Pembrolizumab, also known as MK-3475, is a humanized IgG4 antibody able to inhibit the PD-1 (programmed cell death 1). PD-1 (Programmed Death Protein 1, CD279) is a transmembrane protein expressed on the surface of immune cells that binds to PD-L1 or PD-L2, inducing apoptosis of T cells and inhibiting immune...

The programmed cell death 1 protein (PD1) is an inhibitory receptor expressed on antigen activated T-cells that plays a critical role in the induction and maintenance of immune tolerance to self-antigens. Upon binding to its ligands CD274/PDCD1L1 (PD-L1) and CD273/PDCD1LG2 (PD-L2), PD1 is phosphorylated within its...

Neutralizing human recombinant monoclonal antibody (clone 1B8, IgG1 subclass) recognizing the PD-L1 binding region of human PD-1, expressed in a 293 freestyle cell expression system. MW = 50 kDa and 25 kDa for the heavy and light chain portions, respectively.

Programmed cell death protein 1, also called PD-1 or PDCD1 is a protein that in humans is encoded by the PDCD1 gene. This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. By fluorescence in situ hybridization, the PDCD1 gene is mapped to 2q37.3. This protein is expressed in pro-B-cells...