NALP3 (CIAS1) Human Recombinant Protein

NALP3 (CIAS1) Human Recombinant Protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
BPS-80117 5 µg - -

3 - 15 business days*

Human NLR Family Pyrin Domain Containing 3 (NLRP3), also known as NALP3, Cold Autoinflammatory... more
Product information "NALP3 (CIAS1) Human Recombinant Protein"
Human NLR Family Pyrin Domain Containing 3 (NLRP3), also known as NALP3, Cold Autoinflammatory Syndrome 1 Protein (CIAS1), cryopyrin and PYPAF1 (Genbank Accession No. NM_004895), a.a. 2-1036(end) with N-terminal His-FLAG-tag, expressed in a baculovirus infected Sf9 cell expression system. MW = 120 kDa (calculated). Protein function: May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18. [The UniProt Consortium]
Keywords: NLRP3, CLR1.1, C1orf7, Cryopyrin, Caterpiller protein 1.1, PYRIN-containing APAF1-like protein 1, Cold autoinflammatory syndrome 1 protein, Angiotensin/vasopressin receptor AII/AVP-like, NACHT, LRR and PYD domains-containing protein 3
Supplier: BPS Bioscience
Supplier-Nr: 80117


Application: Protein function studies, Inhibitor screening
Conjugate: No
Expressed in: insect cells
Origin: Human
MW: 120 kD
Purity: >50%

Handling & Safety

Storage: -80°C
Shipping: -20°C (International: -20°C)
Our products are for laboratory research use only: Not for administration to humans!
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