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NALP3 (delPYD), FLAG-Tag
NALP3 (delPYD), FLAG-Tag

Item number: BPS-100454

Human NLR Family Pyrin Domain Containing 3 (NLRP3), also known as NALP3, Cold Autoinflammatory Syndrome 1 Protein (CIAS1), cryopyrin and PYPAF1, Genbank Accession No. NM_004895, a.a. 134-1036(end) with N-terminal FLAG-tag, expressed in a HEK293 expression system. MW = 105 kDa.
Keywords: NLRP3, C1orf7, CLR1.1, Cryopyrin, Caterpiller protein 1.1, PYRIN-containing APAF1-like protein 1, Angiotensin/vasopressin...
Application: Immunotherapy studies
Reactivity: Human
MW: 120 kD
618.00€ *
Review
Anti-NLRP3/NALP3, clone Cryo-2
Anti-NLRP3/NALP3, clone Cryo-2

Item number: AG-20B-0014-C100

Recognizes mouse and human NLRP3/NALP3. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the...
Keywords: NACHT-, LRR- and PYD-containing Protein 3, NLRP3, Cryopyrin, Cold Autoinflammatory Syndrome 1 Protein
Application: WB
Reactivity: Human , Mouse
308.00€ *
Review
MCC950 . Na
MCC950 . Na

Item number: AG-CR1-3615-M001

Crystalline solid. Soluble in water (10mg/ml), DMSO (10mg/ml), dimethyl formamide or ethanol (1mg/ml). Chemical. CAS: 256373-96-3. Formula: C20H23N2NaO5S. MW: 426.5. Synthetic. Potent, selective and orally available NLRP3 inflammasome inhibitor. Blocks the release of IL-1beta in macrophages primed with LPS and...
Keywords: MCC950, CP-456,773, CRID3, 1-(1,2,3,5,6,7-Hexahydro- s-indacen-4-yl)-3-[4-(1-hydroxy-1-methyl-ethyl)-furan-2-sulfonyl]urea
Application: NLRP3 inflammasome inhibitor
CAS 256373-96-3
MW: 426,5 D
From 39.00€ *
Review
MCC950
MCC950

Item number: Cay17510-1

NOD-like receptor (NLR) pyrin domain-containing protein 3 (NLRP3) senses pathogen-derived, environmental, and host-derived factors and initiates the formation of inflammasomes, complexes involved in complex diseases including multiple sclerosis, type 2 diabetes, Alzheimer's disease, and atherosclerosis. MCC950 is a...
Keywords: CP 456,773, N-[[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-2-furansulfonamide
Application: NLRP3 inhibitor
CAS 210826-40-7
MW: 404.5 D
From 82.00€ *
Review
Anti-NLRP3/NALP3 (mouse), clone Cryo-1
Anti-NLRP3/NALP3 (mouse), clone Cryo-1

Item number: AG-20B-0006-C100

Recognizes mouse NLRP3/NALP3. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like...
Keywords: NACHT-, LRR- and PYD-containing Protein 3, NLRP3, Cryopyrin, Cold Autoinflammatory Syndrome 1 Protein
Application: WB
Reactivity: Mouse
429.00€ *
Review
NALP3 (CIAS1) Human Recombinant Protein
NALP3 (CIAS1) Human Recombinant Protein

Item number: BPS-80117

Human NLR Family Pyrin Domain Containing 3 (NLRP3), also known as NALP3, Cold Autoinflammatory Syndrome 1 Protein (CIAS1), cryopyrin and PYPAF1 (Genbank Accession No. NM_004895), a.a. 2-1036(end) with N-terminal His-FLAG-tag, expressed in a baculovirus infected Sf9 cell expression system. MW = 120 kDa (calculated)....
Keywords: NLRP3, CLR1.1, C1orf7, Cryopyrin, Caterpiller protein 1.1, PYRIN-containing APAF1-like protein 1, Cold autoinflammatory...
Application: Protein function studies, Inhibitor screening
Reactivity: Human
MW: 120 kD
650.00€ *
Review
Monosodium urate (crystals)(2x2mg)
Monosodium urate (crystals)(2x2mg)

Item number: AG-CR1-3950-2002

NLRP3/NALP3 inflammasome activator. Specially crystallized and tested for biological activity. Stimulates the caspase-1 activating NLRP3/NALP3 inflammasome, resulting in the production of active IL-1beta and IL-18.
Keywords: MSU (crystals), Uric acid (crystals)
Application: NLRP3/NALP3 inflammasome activator
CAS 1198-77-2
MW: 167,1 D
From 86.00€ *
Review
Monosodium urate (ready-to-use)
Monosodium urate (ready-to-use)

Item number: AG-CR1-3951-M010

NLRP3/NALP3 inflammasome activator, Specially crystallized and tested for biological activity, Stimulates the caspase-1 activating NLRP3/NALP3 inflammasome, resulting in the production of active IL-1beta and IL-18.
Keywords: MSU (ready-to-use), Uric acid (ready-to-use)
Application: NLRP3/NALP3 inflammasome activator
CAS 1198-77-2
MW: 167,1 D
418.00€ *
Review
Anti-NLRP3 (NALP3)
Anti-NLRP3 (NALP3)

Item number: NSJ-R30750

0.5mg/ml if reconstituted with 0.2ml sterile DI water. NOD-like receptor family pyrin domain containing 3, also known as CIAS1, CRYOPYRIN, NALP3 or PYPAF1, is a protein that in humans is encoded by the NLRP3 gene. The gene encodes a pyrin-like protein expressed predominantly in peripheral blood leukocytes. NLRP3...
Keywords: Anti-NLRP3, Anti-CLR1.1, Anti-C1orf7, Anti-Cryopyrin, Anti-Caterpiller protein 1.1, Anti-PYRIN-containing APAF1-like...
Application: WB, IHC (paraffin), IF/ICC, FC
Reactivity: Human, Mouse, Rat
549.00€ *
Review
NLRP3i
NLRP3i

Item number: Cay30895-1

NLRP3i is an intermediate in the synthesis of glyburide (Cay-15009) and an inhibitor of the NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome. It is selective for NLRP3 over NLRP4 and absent in melanoma 2 (AIM2) inflammasomes at 400 µM. NLRPi inhibits LPS-induced IL-1beta release and...
Keywords: N-[2-[4-(aminosulfonyl)phenyl]ethyl]-5-chloro-2-methoxy-benzamide
Application: NLRP3 inflammasome inhibitor
CAS 16673-34-0
MW: 368.8 D
62.00€ *
Review
Isoliquiritigenin
Isoliquiritigenin

Item number: AG-CN2-0459-M010

Yellow solid. Soluble in DMSO, methanol or ethanol. Anticancer. Apoptosis inducer and cell proliferation inhibitor. Autophagy inducer, Anti-angiogenic. VEGF/VEGFR-2 signaling inhibitor, Antioxidant and antibacterial, AMPK-mediated GSK3beta inhibitor, Anti-inflammatory. Inhibits translocation and activation of...
Keywords: ISL, GU 17, 4,2',4'-Trihydroxychalcone
Application: NLRP3 inflammasome activation inhibitor
CAS 961-29-5
MW: 256,3 D
From 132.00€ *
Review
NLRP3 (NALP3), His-Flag-Tags (HEK293-derived)
NLRP3 (NALP3), His-Flag-Tags (HEK293-derived)

Item number: BPS-100189

Human NLR Family Pyrin Domain Containing 3 (NLRP3), also known as NALP3, Cold Autoinflammatory Syndrome 1 Protein (CIAS1), cryopyrin and PYPAF1 (Genbank Accession No. NM_004895), a.a. 2-1036(end) with N-terminal His-FLAG-tag, expressed in a HEK293 expression system. MW = 120 kDa.
Keywords: NLRP3, C1orf7, CLR1.1, Cryopyrin, Caterpiller protein 1.1, PYRIN-containing APAF1-like protein 1, Angiotensin/vasopressin...
Application: Immunotherapy
Reactivity: Human
MW: 120 kD
618.00€ *
Review
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