130 products were found matching "K12800"!
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Anti-NLRP3/NALP3, clone Cryo-2
Item number: AG-20B-0014-C100
Recognizes mouse and human NLRP3/NALP3. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the...
| Keywords: | NACHT-, LRR- and PYD-containing Protein 3, NLRP3, Cryopyrin, Cold Autoinflammatory Syndrome 1 Protein |
| Application: | IHC, IP, WB, ICC, ChIP |
| Host: | Mouse |
| Species reactivity: | human , mouse |
385.00€
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NEW
Human NLRP3 (NLR Family, Pyrin Domain Containing Protein...
Item number: ELK-ELK5399MS.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human NLRP3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human NLRP3. Next,...
| Keywords: | NLRP3, Cryopyrin, Caterpiller protein 1.1, PYRIN-containing APAF1-like protein 1, Angiotensin/vasopressin receptor... |
| Application: | ELISA |
| Species reactivity: | human |
From 374.00€
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NEW
Human ADH (Antidiuretic Hormone) Microsample ELISA Kit
Item number: ELK-ELK5414MS.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ADH. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ADH. Next,...
| Keywords: | NLRP3, Cryopyrin, Caterpiller protein 1.1, PYRIN-containing APAF1-like protein 1, Angiotensin/vasopressin receptor... |
| Application: | ELISA |
| Species reactivity: | human |
From 374.00€
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CY-09
Item number: TGM-T4164-100mg
Description: CY-09 is an NLRP3 inhibitor. Target: NOD, NOD-like Receptor (NLR). Smiles: OC(=O)c1ccc(C=C2SC(=S)N(Cc3cccc(c3)C(F)(F)F)C2=O)cc1. References: Jiang H, et al. Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders. J Exp Med. 2017 Nov 6,214(11):3219-3238.
| Keywords: | CY 09 |
| Application: | NLRP3 inhibitor |
| CAS | 1073612-91-5 |
| MW: | 423.43 D |
From 52.00€
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NLRP3 Protein, Human, Recombinant (aa 131-704, His)
Item number: TGM-TMPH-04597-100ug
Description: NLRP3 Protein, Human, Recombinant (aa 131-704, His) is expressed in E. coli. The accession number is Q96P20.
| Keywords: | Angiotensin/vasopressin receptor AII/AVP-like , PYRIN-containing APAF1-like protein 1 , C1orf7 , PYPAF1 , NACHT, LRR and... |
| MW: | 73.9 kD |
From 109.00€
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Usnoflast
Item number: Cay45301-1
An NLRP3 inflammasome inhibitor, inhibits ASC oligomerization in LPS-primed and ATP-activated THP-1 cells, reduces nigericin-induced IL-1beta release in LPS-primed THP-1 cells and microglia (IC50s = 11 and 43 nM, respectively), reduces ATP-induced IL-1beta release in LPS-primed human PBMCs (IC50 = 4.5 nM), improves...
| Keywords: | ZYIL1, 2-[(2R)-1E,2-dimethyl-2-pyrrolidinyl]-N-[[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)amino]carbonyl]-ethenesulfonamide |
| Application: | NLRP3 inflammasome inhibitor |
| CAS | 2455519-86-3 |
| MW: | 403.54 D |
From 624.00€
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Emlenoflast
Item number: Cay45477-10
An NLRP3 inflammasome inhibitor. SMILES: O=C(NS(=O)(C1=NN(C(C)C)C=C1)=O)NC2=C3CCCC3=CC4=C2CCC4. InChi Code: InChI=1S/C19H24N4O3S/c1-12(2)23-10-9-17(21-23)27(25,26)22-19(24)20-18-15-7-3-5-13(15)11-14-6-4-8-16(14)18/h9-12H,3-8H2,1-2H3,(H2,20,22,24). InChi Key: MTOUOUSKXWSTAX-UHFFFAOYSA-N
| Keywords: | Inzomelid, IZD-174, MCC7840,... |
| Application: | NLRP3 inflammasome inhibitor |
| CAS | 1995067-59-8 |
| MW: | 388.49 D |
From 480.00€
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Anti-Recombinant NLRP3, clone 10A4
Item number: E-AN301382L.100
This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome...
| Keywords: | Anti-NLRP3, Anti-Cryopyrin, Anti-Caterpiller protein 1.1, Anti-PYRIN-containing APAF1-like protein 1,... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
389.00€
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MCC950 . Na
Item number: AG-CR1-3615-M001
Crystalline solid. Soluble in water (10mg/ml), DMSO (10mg/ml), dimethyl formamide or ethanol (1mg/ml). Chemical. CAS: 256373-96-3. Formula: C20H23N2NaO5S. MW: 426.5. Synthetic. Potent, selective and orally available NLRP3 inflammasome inhibitor. Blocks the release of IL-1beta in macrophages primed with LPS and...
| Keywords: | MCC950, CP-456,773, CRID3, 1-(1,2,3,5,6,7-Hexahydro- s-indacen-4-yl)-3-[4-(1-hydroxy-1-methyl-ethyl)-furan-2-sulfonyl]urea |
| Application: | NLRP3 inflammasome inhibitor |
| CAS | 256373-96-3 |
| MW: | 426,5 D |
From 39.00€
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MCC950
Item number: Cay17510-1
MCC950 is an inhibitor of NOD-like receptor protein 3 (NLRP3) inflammasome activation. It inhibits ATP-induced IL-1beta release in LPS-primed mouse bone marrow-derived macrophages (BMDMs, IC50 = 7.5 nM), as well as cytosolic LPS-induced IL-1beta release in Pam3CSK4-primed mouse BMDMs at 0.1 and 1 µM, indicating...
| Keywords: | CP 456,773, N-[[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-2-furansulfonamide |
| Application: | NLRP3 inhibitor |
| CAS | 210826-40-7 |
| MW: | 404.5 D |
From 126.00€
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NALP3 (delPYD), FLAG-Tag
Item number: BPS-100454
Human NLR Family Pyrin Domain Containing 3 (NLRP3), also known as NALP3, Cold Autoinflammatory Syndrome 1 Protein (CIAS1), cryopyrin and PYPAF1, Genbank Accession No. NM_004895, a.a. 134-1036(end) with N-terminal FLAG-tag, expressed in a HEK293 expression system. MW = 105 kDa.
| Keywords: | CLR1.1, Cryopyrin, Caterpiller protein 1.1, PYRIN-containing APAF1-like protein 1, Angiotensin/vasopressin receptor... |
| Application: | Immunotherapy studies |
| Expressed in: | human cells |
| Origin: | human |
| MW: | 120 kD |
760.00€
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Human NALP3 / Cryopyrin ELISA Kit
Item number: ARG82259.96
Protein function: As the sensor component of the NLRP3 inflammasome, plays a crucial role in innate immunity and inflammation. In response to pathogens and other damage-associated signals, initiates the formation of the inflammasome polymeric complex, made of NLRP3, PYCARD and CASP1 (and possibly CASP4 and CASP5)....
| Keywords: | NLRP3, CLR1.1, C1orf7, Cryopyrin, Caterpiller protein 1.1, PYRIN-containing APAF1-like protein 1, Angiotensin/vasopressin... |
| Application: | ELISA |
| Species reactivity: | human |
1,463.00€
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