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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-PKSH033845.10 | 10 µg | - |
7 - 16 business days* |
129.00€
|
|||
E-PKSH033845.50 | 50 µg | - |
7 - 16 business days* |
384.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein Construction: Recombinant Human Granulocyte Colony-stimulating Factor Receptor is... more
Product information "G-CSFR/CD114/CSF3R (C-Fc) (recombinant human)"
Protein Construction: Recombinant Human Granulocyte Colony-stimulating Factor Receptor is produced by our Mammalian expression system and the target gene encoding Glu25-His627 is expressed with a Fc tag at the C-terminus. Sequence: Glu25-His627. Fusion tag: C-Fc Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 110-130 kDa. Protein function: Granulocyte Colony Stimulating Factor Receptor (G-CSFR), also known as CD114, the protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Mutations in the G-CSF receptor leading to carboxy-terminal truncation transduce hyperproliferative growth responses, and are implicated in the pathological progression of severe congenital neutropenia (SCN) to acute myelogenous leukemia (AML). Additionally, autocrine/paracrine stimulation of G-CSFR may be important in the biology of solid tumors, including metastasis. Protein function: Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface. [The UniProt Consortium]
Keywords: | CD114, GCSFR, CSF3R, G-CSF-R, G-CSF receptor, Granulocyte colony-stimulating factor receptor, Recombinant Human G-CSFR/CD114/CSF3R (C-Fc) |
Supplier: | Elabscience |
Supplier-Nr: | E-PKSH033845 |
Properties
Conjugate: | No |
Host: | Human cells |
Species reactivity: | human |
MW: | 93.7 kD |
Format: | Lyophilized |
Database Information
KEGG ID : | K05061 | Matching products |
UniProt ID : | Q99062 | Matching products |
Gene ID | GeneID 1441 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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