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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
C2277-06J1.100 | 100 µg | - | - |
3 - 19 business days* |
644.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
D26 is a complex enzyme expressed on the surface of most cell types and is a serine exopeptidase... more
Product information "CD26, Recombinant, Human, His-tag, Hi-5 (DPP IV, Dipeptidyl Peptidase IV, DPPIV, ADABP, ADCP2, TP103"
D26 is a complex enzyme expressed on the surface of most cell types and is a serine exopeptidase that cleaves x-proline dipeptides from the N-terminus of polypeptides. DPP4 protein is associated with intracellular signal transduction, apoptosis and plays an important role in tumor biology. There are at least 63 substrates which can bind specifically to DPP4 enzyme including growth factors, chemokines, neuro peptides. Furthermore, DPP4 plays a major role in glucose metabolism by cleaving incretins such as glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). Recombinant protein corresponding to aa39-766 of human CD26, with a C-terminal His-tag, expressed in high-5 cells using baculovirus expression system. , Theoretical Molecular Weight: 86.4kD (746aa), (SDS-PAGE under denatured condition, apparent molecular weight of glycosylated rhDPP-4 protein will be appeared at approximately 90kD). Biological activity: > 50units/mg, Unit Definition: One unit will hydrolyze 1umole of p-nitroaniline per minute at pH 8.0, at 37°C using 1mM of Gly-Pro p-nitroanilde as a substrate. Applications: Useful for the study of enzyme kinetics, screening inhibitors and selectivity profiling. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | DPP4, ADCP2, EC=3.4.14.5 |
Supplier: | United States Biological |
Supplier-Nr: | C2277-06J1 |
Properties
Conjugate: | No |
Species reactivity: | human |
Format: | Highly Purified |
Database Information
KEGG ID : | K01278 | Matching products |
UniProt ID : | P27487 | Matching products |
Gene ID | GeneID 1803 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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