106 products were found matching "P27487"!

DPP (IV) inhibitors have emerged as a new class of oral antidiabetic agents. These inhibitors promote glucose homeostasis by inhibiting degradation of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) by DPP (IV). GLP-1 extends the action of insulin while suppressing the release...

DPP4/CD26 is a type II transmembrane glycoprotein expressed ubiquitously in most tissues and different cell types. The protein has a short cytoplasmic domain, transmembrane domain, a flexible stalk fragment and extracellular fragment. Both the catalytic peptide hydrolase domain and the beta-propeller ligand binding...

Protein function: Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation...

Active human DPP4 (GenBank Accession No. NM_001935), (amino acids 29-end) with C-terminal His tag, MW=89.1 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

The DPP4 Fluorescent Activity Assay kit is designed to measure DPP4 activity using purified DPP4 or DPP4 extracts. It comes in a convenient 96-well format, with purified DPP4 enzyme, DPP4 substrate, and DPP4 assay buffer for 100 enzyme reactions. The key to DPP4 Fluorescent Activity Assay is the fluorogenic...

Human CD26 is a T cell activation antigen which can be associated with costimulation. The significance of the dipeptidyl peptidase IV activity remains unknown. Characterization of adenosine deaminase binding to CD26 suggests an important immunoregulatory role. Soluble CD26 serum levels are predictive for colorectal...

Dipeptidyl peptidase 4 (DPP-4), also known as CD26, is a type II transmembrane glycoprotein with a major role in glucose metabolism. It is composed of a short cytoplasmic tail, a transmembrane domain, and a large extracellular domain, which contains a flexible stalk, glycosylation- and cysteine-rich regions, and a...

Human CD26 is a T cell activation antigen which can be associated with costimulation. The significance of the dipeptidyl peptidase IV activity remains unknown. Characterization of adenosine deaminase binding to CD26 suggests an important immunoregulatory role. Soluble CD26 serum levels are predictive for colorectal...

Human CD26 is a T cell activation antigen which can be associated with costimulation. The significance of the dipeptidyl peptidase IV activity remains unknown. Characterization of adenosine deaminase binding to CD26 suggests an important immunoregulatory role. Soluble CD26 serum levels are predictive for colorectal...

Human CD26 is a T cell activation antigen which can be associated with costimulation. The significance of the dipeptidyl peptidase IV activity remains unknown. Characterization of adenosine deaminase binding to CD26 suggests an important immunoregulatory role. Soluble CD26 serum levels are predictive for colorectal...

Human CD26 is a T cell activation antigen which can be associated with costimulation. The significance of the dipeptidyl peptidase IV activity remains unknown. Characterization of adenosine deaminase binding to CD26 suggests an important immunoregulatory role. Soluble CD26 serum levels are predictive for colorectal...

Protein function: Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation...