- Search results for K01278
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256 products were found matching "K01278"!
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Item number: Cay700210-96
DPP (IV) inhibitors have emerged as a new class of oral antidiabetic agents. These inhibitors promote glucose homeostasis by inhibiting degradation of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) by DPP (IV). GLP-1 extends the action of insulin while suppressing the release...
Keywords: | Dipeptidyl peptidase IV |
Application: | DPP (IV) inhibitor screening |
Species reactivity: | human |
476.00€
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Item number: E-AN006030L.100
Dipeptidyl peptidase-4 (DPP4) or adenosine deaminase complexing protein 2 (ADCP 2) or T-cell activation antigen CD26 is a serine exopeptidase belonging to the S9B protein family that cleaves X-proline dipeptides from the N-terminus of polypeptides, such as chemokines, neuropeptides, and peptide hormones. The enzyme...
Keywords: | Anti-ADCP2, DPP4/CD26 Polyclonal antibody |
Application: | WB |
Host: | Rabbit |
Species reactivity: | mouse,rat |
From 109.00€
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Item number: Cay41117-10
DBPR108 is an inhibitor of dipeptidyl peptidase 4 (DPP-4, IC50 = 0.015 µM). It is selective for DPP-4 over DPP-8 and DPP-9 (IC50s = >50 µM for both). DBPR108 (10 mg/kg) increases plasma levels of glucagon-like peptide 1 (GLP-1) and insulin in rats. It reduces blood glucose levels in an oral glucose tolerance test in...
Keywords: | Prusogliptin, 1-[2S-[[1,1-dimethyl-3-oxo-3-(1-pyrrolidinyl)propyl]amino]acetyl]-4S-fluoro-2-pyrrolidinecarbonitrile |
Application: | DPP-4 inhibitor |
CAS | 1186426-66-3 |
MW: | 324.4 D |
From 136.00€
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Item number: TGM-T68652-100mg
Description: Carmegliptin dihydrochloride is the salt form of Camegliptin (free base), also known as RG-1579 and RO4876904, a dipeptidyl peptidase IV (DPP-4) inhibitor potentially for the treatment of type 2 diabetes. Target: Others. Smiles: Cl.Cl.[H][C@@]12C[C@H](N)[C@H](CN1CCc1cc(OC)c(OC)cc21)N1C[C@@H](CF)CC1=O
Application: | Targets dipeptidyl-peptidase 4 [EC:3.4.14.5] (DPP4, CD26) |
CAS | 813452-14-1 |
MW: | 450.38 D |
From 2,421.00€
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Item number: TGM-T7133-100mg
Description: Anagliptin (SK-0403) is a potent inhibitor of DPP-4 (IC50 of 3.8 nM) used in the treatment of type 2 diabetes mellitus. Target: DPP-4, Proteasome. Smiles: Cc1cc2ncc(cn2n1)C(=O)NCC(C)(C)NCC(=O)N1CCC[C@H]1C#N. References: Ervinna N, et al. Anagliptin, a DPP-4 inhibitor, suppresses proliferation of...
Keywords: | SK-0403 |
Application: | Targets dipeptidyl-peptidase 4 [EC:3.4.14.5] (DPP4, CD26) |
CAS | 739366-20-2 |
MW: | 383.45 D |
From 40.00€
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Item number: TGM-T6999-100mg
Description: Teneligliptin hydrobromide (MP-513 (hydrobromide)) is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor, competitively inhibited human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50 values of approximately 1 nM. Target: Others, Proteasome, DPP-4. Smiles:...
Keywords: | Teneligliptin hydrobromide anhydrous, MP-513 (hydrobromide) |
Application: | Targets dipeptidyl-peptidase 4 [EC:3.4.14.5] (DPP4, CD26) |
CAS | 906093-29-6 |
MW: | 628.86 D |
From 31.00€
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Item number: TGM-T7369-100mg
Description: Gemigliptin (LC15-0444) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor(KD : 7.25 nM.). Target: DPP-4, Proteasome. Smiles: N[C@H](CN1CC(F)(F)CCC1=O)CC(=O)N1CCc2c(C1)nc(nc2C(F)(F)F)C(F)(F)F. References: Choi S Y , Ryu H M , Oh E J , et al. Dipeptidyl peptidase-4 inhibitor gemigliptin protects...
Keywords: | LC15-0444 |
Application: | Targets dipeptidyl-peptidase 4 [EC:3.4.14.5] (DPP4, CD26) |
CAS | 911637-19-9 |
MW: | 489.36 D |
From 34.00€
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Item number: TGM-T7369L-10mg
Description: Gemigliptin Tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4). It has an IC50 of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate exhibits potent anti-glycation properties. Target: Proteasome, DPP-4. Smiles:...
Keywords: | LC15-0444 tartrate |
Application: | DPP-4 inhibitor |
CAS | 1374639-74-3 |
MW: | 639.45 D |
From 34.00€
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Item number: TGM-T78410-100mg
Description: Gly-Pro-AMC hydrobromide (Gly-Pro-AMC HCl) is a specific fluorescent dye used in cytofluorescence assays to detect Dipeptidyl peptidase IV (DPP-IV) activity. Smiles: CC=1C=2C(=CC(NC(=O)[C@H]3N(C(CN)=O)CCC3)=CC2)OC(=O)C1.Br. References: Gallego M, et al. Dipeptidyl peptidase IV inhibitory peptides...
Keywords: | Gly-Pro-AMC HCl |
Application: | Substrate for dipeptidylaminopeptidase IV |
CAS | 115035-46-6 |
MW: | 410.26 D |
From 67.00€
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Item number: TGM-T84970-10mg
Description: H-Gly-Pro-Hyp-OH, a peptide dipeptidyl peptidase 4 (DPP-4) inhibitor with an inhibition concentration (IC50) of 2.51 mM, effectively hinders the activity of the DPP-4 enzyme. Target: Others. Smiles: C(C)(O)=O.C(=O)(N1[C@H](C(O)=O)C[C@@H](O)C1)[C@H]2N(C(CN)=O)CCC2
Keywords: | H-GP-Hyp-OH |
Application: | Peptide DPP-4 inhibitor |
CAS | 103192-50-3 |
MW: | 345.35 D |
Please request pricing for this article.
Item number: TGM-TMPY-00221-100ug
Description: DPP4/CD26 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 112.9 kDa and the accession number is P28843.
Keywords: | THAM, Cd26, Dpp-4, dipeptidylpeptidase 4 |
MW: | 112.9 kD |
From 219.00€
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Item number: TGM-TMPY-00074-50ug
Description: DPP4/CD26 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85.9 kDa and the accession number is P28843.
Keywords: | THAM, Cd26, dipeptidylpeptidase 4, Dpp-4 |
MW: | 85.9 kD |
599.00€
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