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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| Cay44015-1 | 1 mg | - |
6 - 10 business days* |
193.00€
|
|||
| Cay44015-5 | 5 mg | - |
6 - 10 business days* |
909.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Z-VEID-FMK is a peptide inhibitor of caspase-3 and -6 (apparent IC50s = 45. and 128. nM,... more
Product information "Z-VEID-FMK"
Z-VEID-FMK is a peptide inhibitor of caspase-3 and -6 (apparent IC50s = 45. and 128. nM, respectively). It decreases lamin cleavage induced by caspase-6 in a cell-free assay (IC50 = 45 µM). Z-VEID-FMK (160 µM) decreases apoptosis in primary human erythroblasts cultured in erythropoietin-deficient media. It increases survival of primary rat retinal whole-mount cultures when used at a concentration of 10 µM. Intraocular administration of Z-VEID-FMK decreases apoptosis in retinal ganglion cells and increases axonal regeneration in a rat model of optic nerve crush. InChI: InChI=1S/C31H45FN4O10/c1-7-19(4)27(30(42)34-22(23(37)16-32)15-25(39)45-6)35-28(40)21(13-14-24(38)44-5)33-29(41)26(18(2)3)36-31(43)46-17-20-11-9-8-10-12-20/h8-12,18-19,21-22,26-27H,7,13-17H2,1-6H3,(H,33,41)(H,34,42)(H,35,40)(H,36,43)/t19-,21-,22-,26-,27-/m0/s1 InChIKey: YPIHFMWAHMPACV-IREHUOSBSA-N SMILES: O=C(OCC1=CC=CC=C1)N[C@@H](C(C)C)C(N[C@@H](CCC(OC)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(CF)=O)CC(OC)=O)=O)=O)=O
| Keywords: | Cbz-Val-Glu(OMe)-Ile-Asp(OMe)-CH2F, methyl (5S,8S,11S,14S)-11-((S)-sec-butyl)-14-(2-fluoroacetyl)-5-isopropyl-8-(3-methoxy-3-oxopropyl)-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 44015 |
Properties
| Application: | Caspase-3 / caspase-6 peptide inhibitor |
| Conjugate: | No |
| MW: | 652.72 D |
| Formula: | C31H45FN4O10 |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 210344-96-0| Matching products |
| KEGG ID : | K02187 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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