S-2238 (hydrochloride)

S-2238 is a chromogenic substrate for thrombin. Upon enzymatic cleavage, p-nitroanilide (pNA) is released which can be quantified by colorimetric detection at 405 nm as a measure of thrombin activity.Formal Name: D-phenylalanyl-(2S)-2-piperidinecarbonyl-N-(4-nitrophenyl)-L-argininamide, monohydrochloride. CAS Number: 160192-34-7. Synonyms: H-D-Phe-Pip-Arg-pNA, D-Phe-Piperidinecarbonyl-Arg-p-nitroanilide. Molecular Formula: C27H36N8O5 . HCl. Formula Weight: 589.1. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble. lambdamax: 313 nm. SMILES: O=N(C(C=C1)=CC=C1NC([C@H](CCCNC(N)=N)NC([C@H]2N(CCCC2)C([C@H](N)CC3=CC=CC=C3)=O)=O)=O)=O.Cl. InChi Code: InChI=1S/C27H36N8O5.ClH/c28-21(17-18-7-2-1-3-8-18)26(38)34-16-5-4-10-23(34)25(37)33-22(9-6-15-31-27(29)30)24(36)32-19-11-13-20(14-12-19)35(39)40,/h1-3,7-8,11-14,21-23H,4-6,9-10,15-17,28H2,(H,32,36)(H,33,37)(H4,29,30,31),1H/t21-,22+,23+,/m1./s1. InChi Key: YEOVJZRYPLLHJL-FMVQVTEISA-N.