PKCtheta Pseudosubstrate Inhibitor

PKCtheta pseudosubstrate inhibitor is a synthetic peptide that corresponds to amino acid residues of the pseudosubstrate domain of protein kinase Ctheta (PKCtheta). It selectively, reversibly, and substrate-competitively inhibits PKCtheta activity and, thus, is used to delineate the signaling functions of PKCtheta, which are thought to be involved in several autoimmune disorders.Formal Name: H-leucyl-histidyl-glutamyl-arginyl-glycyl-alanyl-isoleucyl-lysyl-glutamyl-alanyl-arginyl-arginyl-tryptophyl-arginyl-lysyl-leucine. Synonyms: Protein Kinase C theta Pseudosubstrate Inhibitor. Molecular Formula: C95H165N39O20. Formula Weight: 2173.6. Purity: >95%. Formulation: (Request formulation change), A lyophilized powder. Solubility: DMF: 16 mg/ml, DMSO: 20 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: [H]N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@H](C(N[C@]([C@H](CC)C)([H])C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H]. InChi Code: InChI=1S/C95H165N39O20/c1-9-51(6)74(134-76(139)52(7)120-73(137)47-118-78(141)59(25-16-36-112-91(101)102)123-82(145)63(27-18-38-114-93(105)106)126-86(149)67(31-33-72(100)136)129-88(151)69(44-55-46-111-48-119-55)131-77(140)57(98)41-49(2)3)89(152)130-61. InChi Key: OWVMIDKPSPZRQE-JPMNJRGHSA-N.