Substrates and Inhibitors

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Beta-Ala-R110-ML
Beta-Ala-R110-ML

Item number: ABD-13205

Excitation (nm): 500. Emission (nm) 522. Fluorometric methods based on the peptide substrates labeled with cleavable fluorophores have been widely used for assaying various proteases. The two dominant classes are AMC-based (coumarin dye) and R110-based (rhodamine 110) substrates. AMC substrates are much less...
Application: Fluorogenic peptide substrate, Protease assays
196.00€ *
Review
Ac-LKKR-AMC
Ac-LKKR-AMC

Item number: ABD-13446

Excitation (nm): 341. Emission (nm): 441. Ac-Leu-Lys-Lys-Arg-AMC is a fluorogenic aminopeptidase and endopeptidase substrate. It might be used as a fluorogenic probe for detecting thrombin and metacaspases. Metacaspases are found in plants, fungi, and protozoa. They are cysteine-proteases and are distantly related...
Application: Fluorogenic aminopeptidase / endopeptidase substrate
MW: 1084.99 D
261.00€ *
Review
Z-DEVD-aminoluciferin
Z-DEVD-aminoluciferin

Item number: ABD-13211

Ex: 362 nm. Em: 499 nm. Solvent: DMSO. Z-DEVD-aminoluciferin is a luminogenic substrate that measures caspase-3 and -7 activities in apoptotic cells. Caspases, a family of aspartate-specific cysteine proteases, are key regulators of apoptosis, orchestrating the initiation and execution of cellular disassembly...
Keywords: CASP3, CPP32, SCA-1, CPP-32, CASP-3, Apopain, Caspase-3, EC=3.4.22.56, MCH3, CASP7, CMH-1, CASP-7, ICE-LAP3, Caspase-7,...
Application: Luminogenic substrate
MW: 871.89 D
255.00€ *
Review
EGFR Peptide (human, mouse) (trifluoroacetate salt)
EGFR Peptide (human, mouse) (trifluoroacetate salt)

Item number: Cay36896-500

EGFR peptide is a peptide substrate of PKC that corresponds to an amino acid sequence from the intracellular region of EGFR. It has been used to monitor PKC activity in primary bovine retinal endothelial cells. Unlike EGFR peptide (myristoylated) (Cay-36897), EGFR peptide does not inhibit PKC when used at a...
Keywords: Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH, Epidermal Growth Factor Receptor Peptide,...
Application: PKC peptide substrate
MW: 1098.4 D
305.00€ *
Review
Retatrutide
Retatrutide

Item number: BPS-82638-1

Retatrutide (LY3437943) is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R) of interest in the treatment of obesity.
Application: GCGR/GIPR/GLP-1R triple agonist peptide
MW: 4731,3 D
From 816.00€ *
Review
Exendin-4 (Exenatide)
Exendin-4 (Exenatide)

Item number: BPS-82640-1

Exendin-4 (Exenatide), a 39 amino acid peptide, is a long-acting GLP-1 ( glucagon-like peptide-1) receptor agonist that promotes insluin secretion, and of potential use in the treatment of MASH.
Application: Long-acting GLP-1 ( glucagon-like peptide-1) receptor agonist
MW: 4186,57 D
From 517.00€ *
Review
Lixisenatide
Lixisenatide

Item number: BPS-82641-1

Lixisenatide is a GLP-1 (glucagon-like peptide-1) receptor agonist used in the treatment of type 2 diabetes (T2D). Lixisenatide inhibits the inflammatory response through down regulation of proinflammatory cytokines, and blocks of cellular signaling pathways.
Application: GLP-1 (glucagon-like peptide-1) receptor agonist
MW: 4858,49 D
From 635.00€ *
Review
Semaglutide
Semaglutide

Item number: BPS-82647-1

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist. Semaglutide is used in the treatment of type 2 diabetes (T2D) and obesity.
Application: Glucagon-like peptide-1 (GLP-1) receptor agonist
CAS 910463-68-2
From 507.00€ *
Review
36 from 36 pages