TLK117

Description: TLK117 is an inhibitor of GSTs that reduces the severity of pulmonary fibrosis and can be used to study idiopathic pulmonary fibrosis. Target: GST, Glutathione Peroxidase. Smiles: [C@H](NC([C@@H](NC(CC[C@@H](C(O)=O)N)=O)CSCC1=CC=CC=C1)=O)(C(O)=O)C2=CC=CC=C2. References: McMillan DH, et al. Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase pi. JCI Insight. 2016 Jun 2,1(8):e85717.