Sulfo-SMCC (sodium salt)

Sulfo-SMCC is a water-soluble protein cross-linking reagent that contains an anime-reactive sulfo-N-hydroxysuccinimide (sulfo-NHS) ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. It has been used to conjugate anti-programmed cell death ligand 1 (PD-L1) antibodies to the surface of platelets to induce antitumor immunity in xenograft models, as well as to conjugate Golgi-targeting peptides to platelet microparticle-mimetic nanoplatforms for the delivery of all-trans retinoic acid (Cay-11017) to isolated human synovial fibroblasts from patients with rheumatoid arthritis.Formal Name: 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-cyclohexanecarboxylic acid, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester, monosodium salt. CAS Number: 92921-24-9. Synonyms: Sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate. Molecular Formula: C16H17N2O9S . Na. Formula Weight: 436.4. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Acetonitrile: soluble, Water: soluble. SMILES: O=C1C=CC(N1CC2CCC(CC2)C(ON3C(CC(S(=O)([O-])=O)C3=O)=O)=O)=O.[Na+]. InChi Code: InChI=1S/C16H18N2O9S.Na/c19-12-5-6-13(20)17(12)8-9-1-3-10(4-2-9)16(23)27-18-14(21)7-11(15(18)22)28(24,25)26,/h5-6,9-11H,1-4,7-8H2,(H,24,25,26),/q,+1/p-1. InChi Key: VUFNRPJNRFOTGK-UHFFFAOYSA-M.