Substance P (8-11) (trifluoroacetate salt)

Substance P (8-11) is a peptide fragment of substance P (Cay-24035). It promotes corneal epithelial wound healing in combination with insulin-like growth factor 1 (IGF-1) in diabetic rats with streptozotocin-induced diabetes. Inner ear infusion of substance P (8-11), in combination with the IGF-1 tetrapeptide SSSR, increases the number of lateral circular canal synaptic ribbons, decreases the incidence of spontaneous nystagmus, and stabilizes the vestibulo-ocular reflex in a guinea pig model of vestibular disorder induced by (R,S)-AMPA (Cay-14571). InChI: InChI=1S/C22H35N5O4S.C2HF3O2/c1-14(2)11-18(22(31)27-17(20(24)29)9-10-32-3)26-19(28)13-25-21(30)16(23)12-15-7-5-4-6-8-15,3-2(4,5)1(6)7/h4-8,14,16-18H,9-13,23H2,1-3H3,(H2,24,29)(H,25,30)(H,26,28)(H,27,31),(H,6,7)/t16-,17-,18-,/m0./s1, InChIKey: LFNCTBJROMLLTO-UVJOBNTFSA-N, SMILES: CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC(CNC([C@@H](N)CC1=CC=CC=C1)=O)=O)=O.OC(C(F)(F)F)=O