SARS-CoV-2 (ORF3a) Peptide Pool

SARS-CoV-2 (ORF3a) Peptide Pool
Item number Size Datasheet Manual SDS Delivery time Quantity Price
PE-LB01785.1 1 set (15 nmol (~25µg)/peptide for 2.5 x 10^8 cells) -

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265.00€
 
Pool of 66 overlapping peptides derived from a peptide scan (15mers with 11 aa overlap) through... more
Product information "SARS-CoV-2 (ORF3a) Peptide Pool"
Pool of 66 overlapping peptides derived from a peptide scan (15mers with 11 aa overlap) through Protein ORF3a (UniProt: P0DTC3) of SARS-CoV-2 (Severe Acute Respiratory Syndrome-related coronavirus 2) for T cell assays (e.g. ELISPOT). One unit allows the stimulation of 2,5 x 10^8 cells. Protein function: Plays a role in viral egress via lysosomal trafficking (PubMed:33157038, PubMed:33422265). Forms homotetrameric ion channels (viroporin) localized at endosomes and lysosomes, that may induce deacidification of lysosomes, allowing safe egress of virions via lysosomal trafficking (PubMed:33157038, PubMed:33422265,PubMed:34158638). Also blocks autolysosomes formation by binding and sequestering the host component VPS39 for homotypic fusion and protein sorting (HOPS) on late endosomes. This prevents fusion of autophagosomes with lysosomes, disrupting autophagy and facilitating virus egress (PubMed:33422265). [The UniProt Consortium]
Keywords: 3a, ORF3a, Protein X1, Protein 3a, Protein U274, ORF3a protein, Accessory protein 3a
Supplier: peptides and elephants
Supplier-Nr: LB01785

Properties

Application: T-cell assays, Immune monitoring, antigen spec. T-cell stimulation, T-cell expansion, cell. immune resp
Conjugate: No
Species reactivity: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
Format: Lyophilized

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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