PAR4 (1-6) amide (human) (trifluoroacetate salt)

PAR4 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 4 (PAR4) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR4 and residues 48-53 of the full-length sequence. It induces contractions in isolated rat gastric longitudinal muscle tissue and endothelium-dependent relaxation of precontracted rat aortic rings (EC50s = 300-400 µM).Formal Name: glycyl-L-tyrosyl-L-prolylglycyl-L-glutaminyl-L-valinamide, trifluoroacetate salt. Synonyms: GQV-NH2, GYPGQV-NH2, H-Gly-Tyr-Pro-Gly-Gln-Val-NH2. Molecular Formula: C28H42N8O8 . XCF3COOH. Formula Weight: 618.7. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: 1 mg/ml. SMILES: NC([C@H](C(C)C)NC([C@H](CCC(N)=O)NC(CNC([C@@H]1CCCN1C([C@@H](NC(CN[H])=O)CC2=CC=C(O)C=C2)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F. InChi Code: InChI=1S/C28H42N8O8.C2HF3O2/c1-15(2)24(25(31)41)35-26(42)18(9-10-21(30)38)33-23(40)14-32-27(43)20-4-3-11-36(20)28(44)19(34-22(39)13-29)12-16-5-7-17(37)8-6-16,3-2(4,5)1(6)7/h5-8,15,18-20,24,37H,3-4,9-14,29H2,1-2H3,(H2,30,38)(H2,31,41)(H,32,43)(H,33,40)(H,34,39)(H,35,42),(H,6,7)/t18-,19-,20-,24-,/m0./s1. InChi Key: MMOCFXQKCYLLRG-XESNDDQGSA-N.