Oligopeptide-20 (acetate)

Oligopeptide-20 is a peptide that corresponds to amino acids 55-66 of mature insulin-like growth factor 1 (IGF-1). It increases growth of keratinocytes and fibroblasts and the levels of procollagen, laminin, and fibronectin in keratinocytes. Oligopeptide-20 (100 mg/animal), as part of a peptide nanosome-based skin cream formulation, increases thickness of the keratinocyte and epidermal skin layer in mice.. SMILES: OC(C=C1)=CC=C1C[C@H](NC([C@H](CCSC)NC([C@H](CCC(O)=O)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@@H](N)CCCNC(N)=N)=O)=O)=O)=O)=O)C(N[C@@H](CS)C(N[C@@H](C)C(N2[C@@H](CCC2)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N3[C@@H](CCC3)C(O)=O)=O)=O)=O)=O)=O)=O.CC(O)=O. InChi Code: InChI=1S/C65H109N19O16S2.C2H4O2/c1-35(2)31-45(79-53(89)41(15-10-27-73-65(70)71)75-52(88)40(67)13-9-26-72-64(68)69)56(92)76-42(22-23-51(86)87)54(90)77-43(24-30-102-6)55(91)80-47(33-38-18-20-39(85)21-19-38)58(94)82-48(34-101)59(95)74-37(5)61(97)83-28-11-16-49(83)60(96)81-46(32-36(3)4)57(93)78-44(14-7-8-25-66)62(98)84-29-12-17-50(84)63(99)100,1-2(3)4/h18-21,35-37,40-50,85,101H,7-17,22-34,66-67H2,1-6H3,(H,74,95)(H,75,88)(H,76,92)(H,77,90)(H,78,93)(H,79,89)(H,80,91)(H,81,96)(H,82,94)(H,86,87)(H,99,100)(H4,68,69,72)(H4,70,71,73),1H3,(H,3,4)/t37-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,/m0./s1. InChi Key: OJQXXHLHCNIJJS-CHABMUQESA-N