Obtustatin

Obtustatin
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-TP1974-1mg 1 mg

7 - 10 business days*

840.00€
 
Description: Highly potent integrin alpha1beta1 inhibitor (IC50 = 0.8 nM for alpha1beta1 binding... more
Product information "Obtustatin"
Description: Highly potent integrin alpha1beta1 inhibitor (IC50 = 0.8 nM for alpha1beta1 binding to type IV collagen). Selective for alpha1beta1 over alpha2beta1, alphaIIbbeta3, alphavbeta3, alpha4beta1, alpha5beta6, alpha9beta1 and alpha4beta7. Inhibits FGF2-stimulated angiogenesis in the chicken chorioallantoic model. Displays antitumor efficacy in a synergistic mouse model of Lewis lung carcinoma, blocks human melanoma growth in nude mice. References: Moreno-Murciano et al (2003) Amino acid sequence and homology modeling of obtustatin, a novel non-RGD-containing short disintegrin isolated from the venom of Vipera lebetina obtusa. Protein Sci. 12 366 PMID:
Supplier: TargetMol
Supplier-Nr: TP1974

Properties

Conjugate: No
MW: 4393.07 D
Formula: C184H284N52O57S8

Database Information

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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