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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay24553-500 | 500 µg | - |
6 - 10 business days* |
212.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Obestatin is a 23-amino acid peptide hormone that is formed by cleavage of the ghrelin and... more
Product information "Obestatin (rat) (trifluoroacetate salt)"
Obestatin is a 23-amino acid peptide hormone that is formed by cleavage of the ghrelin and obestatin prepropeptide. It is secreted by rat stomach, brain, perinatal pancreas, myenteric plexus, Leydig cells, and gastrointestinal mucosa and levels are decreased in rat plasma in response to fasting. Total obestatin levels are also reduced in rat fundus and intestine following treadmill exercise training. Obestatin inhibits release of insulin, somatostatin, and pancreatic polypeptide and stimulates glucagon release from mouse and rat pancreatic islets in vitro in a concentration-dependent manner. In vivo, obestatin (320 µg/kg) reduces food intake without affecting growth hormone or corticosterone release in mice. It also inhibits water intake and dehydration-induced vasopressin secretion in response to a hypovolemic challenge in rats.Formal Name: L-phenylalanyl-L-asparaginyl-L-alanyl-L-prolyl-L-phenylalanyl-L-alpha-aspartyl-L-valylglycyl-L-isoleucyl-L-lysyl-L-leucyl-L-serylglycyl-L-alanyl-L-glutaminyl-L-tyrosyl-L-glutaminyl-L-glutaminyl-L-histidylglycyl-L-arginyl-L-alanyl-L-leucinamide, trifluoroacetate salt. Molecular Formula: C114H174N34O31 . XCF3COOH. Formula Weight: 2516.8. Purity: >95%. Formulation: (Request formulation change), A lyophilized powder. Solubility: Water: 1 mg/ml. SMILES: NC([C@H](CC(C)C)NC([C@@H](NC([C@H](CCCNC(N)=N)NC(CNC([C@@H](NC([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC([C@@H](NC([C@H](CCC(N)=O)NC([C@@H](NC(CNC([C@H](CO)NC([C@H](CC(C)C)NC([C@H](CCCCN)NC([C@@]([C@H](CC)C)([H])NC(CNC([C@H](C(C)C)NC([C@@H](NC([C@@H](NC([C@@H]1CCCN1C([C@@H](NC([C@H](CC(N)=O)NC([C@@H](N[H])CC2=CC=CC=C2)=O)=O)C)=O)=O)CC3=CC=CC=C3)=O)CC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C)=O)=O)CC4=CC=C(O)C=C4)=O)=O)=O)CC5=CN=CN5)=O)=O)=O)C)=O)=O.FC(F)(C(O)=O)F. InChi Code: InChI=1S/C114H174N34O31.C2HF3O2/c1-12-60(8)93(146-90(157)54-128-111(177)92(59(6)7)147-109(175)81(50-91(158)159)143-108(174)78(46-65-25-17-14-18-26-65)144-110(176)83-29-22-42-148(83)113(179)63(11)132-105(171)80(49-87(120)154)139-97(163)69(116)45-64-23-15-13-16-24-64)112(178)137-71(27-19-20-40-115)101(167)140-76(44-58(4)5)106(172)145-82(55-149)99(165)127-52-88(155)130-61(9)95(161)134-72(34-37-84(117)151)103(169)141-77(47-66-30-32-68(150)33-31-66)107(173)136-73(35-38-85(118)152)102(168)135-74(36-39-86(119)153)104(170)142-79(48-67-51-124-56-129-67)98(164)126-53-89(156)133-70(28-21-41-125-114(122)123)100(166)131-62(10)96(162)138-75(94(121)160)43-57(2)3,3-2(4,5)1(6)7/h13-18,23-26,30-33,51,56-63,69-83,92-93,149-150H,12,19-22,27-29,34-50,52-55,115-116H2,1-11H3,(H2,117,151)(H2,118,152)(H2,119,153)(H2,120,154)(H2,121,160)(H,124,129)(H,126,164)(H,127,165)(H,128,177)(H,130,155)(H,131,166)(H,132,171)(H,133,156)(H,134,161)(H,135,168)(H,136,173)(H,137,178)(H,138,162)(H,139,163)(H,140,167)(H,141,169)(H,142,170)(H,143,174)(H,144,176)(H,145,172)(H,146,157)(H,147,175)(H,158,159)(H4,122,123,125),(H,6,7)/t60-,61-,62-,63-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,92-,93-,/m0./s1. InChi Key: IQHGCIXYMXRPAT-JRKJFFPISA-N.
Keywords: | L-phenylalanyl-L-asparaginyl-L-alanyl-L-prolyl-L-phenylalanyl-L-alpha-aspartyl-L-valylglycyl-L-isoleucyl-L-lysyl-L-leucyl-L-serylglycyl-L-alanyl-L-glutaminyl-L-tyrosyl-L-glutaminyl-L-glutaminyl-L-histidylglycyl-L-arginyl-L-alanyl-L-leucinamide, trifluoroa |
Supplier: | Cayman Chemical |
Supplier-Nr: | 24553 |
Properties
Application: | Peptide hormone |
Conjugate: | No |
Species reactivity: | rat |
MW: | 2516.8 D |
Formula: | C114H174N34O31 . XCF3COOH |
Purity: | >95% |
Format: | Solid |
Database Information
KEGG ID : | K05254 | Matching products |
UniProt ID : | Q9QYH7 | Matching products |
Gene ID | GeneID 59301 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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