Neuropeptide Y (1-24) (human, rat) (trifluoroacetate salt)

Neuropeptide Y (NPY) (1-24) is an N-terminal fragment of NPY, a neuropeptide involved in controlling appetite, blood pressure, cardiac contractility, and intestinal secretion. NPY (1-24) does not inhibit [3H]-NPY binding in rat CNS membranes at concentrations up to 10 µM and has no effect on the twitch response of isolated rat vas deferens either alone (EC50 = >1 µM) or when used in combination with the C-terminal fragment NPY (25-36) at a concentration of 1 µM. NPY (1-24) stimulates histamine release from isolated rat peritoneal mast cells with a lower efficacy than full length NPY.Synonyms: NPY (1-24) (human, rat). Molecular Formula: C116H170N30O40S . XCF3COOH. Formula Weight: 2656.8. Purity: >95%. Formulation: (Request formulation change), A lyophilized powder. Solubility: Water: 1 mg/ml. SMILES: NC([C@H](CC(C)C)NC([C@@H](NC([C@H](CO)NC([C@@H](NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCC(O)=O)NC([C@@H](NC([C@@H]1CCCN1C([C@@H](NC([C@@H](NC([C@H](CCC(O)=O)NC(CNC([C@@H]2CCCN2C([C@H](CC(N)=O)NC([C@@H](NC([C@@H]3CCCN3C([C@H](CCCCN)NC([C@H](CO)NC([C@@H]4CCCN4C([C@@H](N[H])CC5=CC=C(O)C=C5)=O)=O)=O)=O)=O)CC(O)=O)=O)=O)=O)=O)=O)CC(O)=O)=O)C)=O)=O)C)=O)=O)CC(O)=O)=O)CCSC)=O)C)=O)=O)CC6=CC=C(O)C=C6)=O)CC7=CC=C(O)C=C7)=O)=O)C)=O)=O.FC(F)(C(O)=O)F. InChi Code: InChI=1S/C116H170N30O40S.C2HF3O2/c1-56(2)45-73(93(120)164)134-96(167)58(4)126-106(177)80(54-147)141-103(174)75(48-63-25-31-66(151)32-26-63)136-102(173)74(47-62-23-29-65(150)30-24-62)135-98(169)68(16-10-39-123-116(121)122)130-94(165)57(3)125-97(168)71(37-44-187-7)132-104(175)77(51-91(160)161)138-100(171)70(34-36-89(156)157)131-95(166)59(5)127-109(180)83-18-12-40-143(83)112(183)60(6)128-101(172)76(50-90(158)159)137-99(170)69(33-35-88(154)155)129-87(153)53-124-108(179)82-17-11-42-145(82)115(186)79(49-86(119)152)140-105(176)78(52-92(162)163)139-110(181)85-20-14-43-146(85)114(185)72(15-8-9-38-117)133-107(178)81(55-148)142-111(182)84-19-13-41-144(84)113(184)67(118)46-61-21-27-64(149)28-22-61,3-2(4,5)1(6)7/h21-32,56-60,67-85,147-151H,8-20,33-55,117-118H2,1-7H3,(H2,119,152)(H2,120,164)(H,124,179)(H,125,168)(H,126,177)(H,127,180)(H,128,172)(H,129,153)(H,130,165)(H,131,166)(H,132,175)(H,133,178)(H,134,167)(H,135,169)(H,136,173)(H,137,170)(H,138,171)(H,139,181)(H,140,176)(H,141,174)(H,142,182)(H,154,155)(H,156,157)(H,158,159)(H,160,161)(H,162,163)(H4,121,122,123),(H,6,7)/t57-,58-,59-,60-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,/m0./s1. InChi Key: KIYUXZYPXHBHMM-NIEXQDNRSA-N.