Mc-Ala-Ala-PAB

Mc-Ala-Ala-PAB is a peptide linker molecule that has been used in the synthesis of antibody-drug conjugates (ADCs). It contains a maleimidocaproyl (Mc) group that can be conjugated to an antibody and a p-aminobenzyl (PAB) spacer that allows the peptide to be linked to active compounds. Mc-Ala-Ala-PAB has been used in the synthesis of ADCs containing glucocorticoid receptor modulators.. SMILES: OCC(C=C1)=CC=C1NC([C@H](C)NC([C@H](C)NC(CCCCCN2C(C=CC2=O)=O)=O)=O)=O. InChi Code: InChI=1S/C23H30N4O6/c1-15(24-19(29)6-4-3-5-13-27-20(30)11-12-21(27)31)22(32)25-16(2)23(33)26-18-9-7-17(14-28)8-10-18/h7-12,15-16,28H,3-6,13-14H2,1-2H3,(H,24,29)(H,25,32)(H,26,33)/t15-,16-/m0/s1. InChi Key: PKHVWJOCRXHNME-HOTGVXAUSA-N