LRRKtide TFA

Description: LRRKtide, a peptide substrate for leucine-rich repeat kinase 2 (LRRK2)â?"an enzyme often mutated in Parkinson's disease patientsâ?"corresponds to amino acids 550-564 of the membrane-organizing extension spike protein (moesin). It serves to identify inhibitors of LRRK2. Smiles: OC(C(F)(F)F)=O.O=C(N[C@H](C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN[H])C(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@@H](CCCCN[H])C(N[C@]([C@H](O)C)([H])C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)([H])[C@@H](C)CC)=O)=O)=O)CC(C)C)=O)=O)=O)=O)=O)=O)=O)=O)CC(C)C)[C@H](CCCNC(N)=N)N[H]