Kallidin (380-389) (human, porcine, bovine) (trifluoroacetate salt)

Kallidin (380-389) is a short-lived kinin peptide involved in inflammation and pain. It binds to bradykinin B2 (IC50 = 0.63 nM) and B1 receptors (Ki = 3.23 nM) and acts as an agonist. It is formed in tissue, including the brain, via cleavage of low molecular weight kininogen (LMWK) by kallikrein serine proteases released in response to injury or inflammation and can be converted into bradykinin. Kallidin levels in interstitial muscle are increased in women with work-related trapezius myalgia.Formal Name: L-lysyl-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-arginine, trifluoroacetate salt. Synonyms: KRPPGFSPFR, Lys-BK, Lysine Bradykinin. Molecular Formula: C56H85N17O12 . XCF3COOH. Formula Weight: 1188.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: slightly soluble, PBS (pH 7.2): 10 mg/ml. SMILES: NCCCC[C@H](N)C(N[C@@H](CCCNC(N)=N)C(N1[C@H](C(N2CCC[C@H]2C(NCC(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CO)C(N4[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCCNC(N)=N)=O)CC5=CC=CC=C5)=O)CCC4)=O)=O)=O)=O)=O)CCC1)=O)=O.OC(C(F)(F)F)=O. InChi Code: InChI=1S/C56H85N17O12.C2HF3O2/c57-24-8-7-18-36(58)46(76)67-37(19-9-25-63-55(59)60)51(81)73-29-13-23-44(73)53(83)72-28-11-21-42(72)49(79)65-32-45(75)66-39(30-34-14-3-1-4-15-34)47(77)70-41(33-74)52(82)71-27-12-22-43(71)50(80)69-40(31-35-16-5-2-6-17-35)48(78)68-38(54(84)85)20-10-26-64-56(61)62,3-2(4,5)1(6)7/h1-6,14-17,36-44,74H,7-13,18-33,57-58H2,(H,65,79)(H,66,75)(H,67,76)(H,68,78)(H,69,80)(H,70,77)(H,84,85)(H4,59,60,63)(H4,61,62,64),(H,6,7)/t36-,37-,38-,39-,40-,41-,42-,43-,44-,/m0./s1. InChi Key: CJWNEIHQAHYJAN-KNJHKARMSA-N.