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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| PE-LB02477.1 | 1 set (15 nmol (~25µg)/peptide for 2.5 x 10^8 cells) | - |
Request delivery time estimate |
323.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein Function: Plays a role in viral genome replication by driving entry of quiescent cells... more
Product information "HPV18 E7 Peptide Pool"
Protein Function: Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha. Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta) (PubMed:26405230) [The Uniprot Consortium]
| Keywords: | E7, Protein E7 |
| Supplier: | peptides and elephants |
| Supplier-Nr: | LB02477 |
Properties
| Conjugate: | No |
| Species reactivity: | HPV-18 |
| Format: | Lyophilized |
Database Information
| KEGG ID : | K21809 | Matching products |
| UniProt ID : | P06788 | Matching products |
Handling & Safety
| Storage: | -20°C (avoid repeat freezing and thawing cycles) |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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