Gastric Inhibitory Peptide, Human, Control Peptide (GIP)

Glucagon is a member of a multigene family comprising of Secretin, Vasoactive Intestinal Peptide (VIP), Gastric Inhibitory Peptide (GIP) and others like Glicentin and Oxyntomodulin (OXM), which differs from glucagon by C-terminal octapeptide. The glucagon precursor contains at least 3 intervening sequences that divide the protein-coding portion into 4 regions corresponding to the signal peptide and part of the N-terminal peptide, the remainder of the N-terminal peptide and glucagon, glucagon-like peptide-1 (GLP1), and GLP2., GIP, Gastric inhibitory polypeptide, also known as glucose-dependent insulinotropic polypeptide (GIP), is a 42-amino acid hormone (chr 17q21.3) that stimulates insulin secretion in the presence of glucose. GIP is derived by proteolytic processing of a 153-residue precursor, preproGIP, it is a member of a family of structurally related hormones that includes secretin, glucagon, vasoactive intestinal peptide, and growth hormone-releasing factor. Source: 10aa peptide of human GIP, Location: Middle region, Cytoplasmic, Species Sequence Homology: Mouse, porcine, rat-90%. Applications: ELISA: Control peptide can be used to coat ELISA plates at 1ug/ml and detected with antibodies (See G2019-02) and antibody blocking experiments. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.