FcIII Peptide (trifluoroacetate salt)

A peptide fusion tag, inhibits binding of the protein A Z domain to IgG Fc (Ki = 25 nM), can be added to the N- or C-terminus of a protein sequence and has been used as an epitope tag on recombinant proteins to facilitate their detection and purification, inclusion of FcIII peptide increases recombinant protein plasma half-life in mice, has been used as a building block in the synthesis of artificial human Fc receptors to facilitate IgG uptake in Jurkat cells. SMILES: O=C1N[C@H](C(N[C@@H]([C@@H](C)O)C(O)=O)=O)CSSC[C@H](NC([C@H](CC(O)=O)N)=O)C(N[C@@H](C)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(N[C@@H](CC4=CN=CN4)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@H]1CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F. InChi Code: InChI=1S/C69H95N17O19S2.C2HF3O2/c1-32(2)19-46-60(95)74-28-53(88)77-45(17-18-54(89)90)61(96)80-47(20-33(3)4)65(100)85-56(34(5)6)68(103)82-49(22-38-26-73-44-16-12-10-14-41(38)44)63(98)84-52(67(102)86-57(36(8)87)69(104)105)30-107-106-29-51(83-59(94)42(70)24-55(91)92)66(101)76-35(7)58(93)78-48(21-37-25-72-43-15-11-9-13-40(37)43)62(97)81-50(64(99)79-46)23-39-27-71-31-75-39,3-2(4,5)1(6)7/h9-16,25-27,31-36,42,45-52,56-57,72-73,87H,17-24,28-30,70H2,1-8H3,(H,71,75)(H,74,95)(H,76,101)(H,77,88)(H,78,93)(H,79,99)(H,80,96)(H,81,97)(H,82,103)(H,83,94)(H,84,98)(H,85,100)(H,86,102)(H,89,90)(H,91,92)(H,104,105),(H,6,7)/t35-,36+,42-,45-,46-,47-,48-,49-,50-,51-,52-,56-,57-,/m0./s1. InChi Key: AWNLGQJGMIVJCI-MRJNCTGSSA-N